Benzyl

About Benzyl

Benzyl is an impurity of Acalabrutinib carrying the CAS registry number 2170801-87-1. With the molecular formula C18H19N5O2, it has a molar mass of 337.4 g/mol. Systematically, it is named benzyl (2S)-2-(8-aminoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Acalabrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Benzyl
Catalogue No.	VQ-028994
CAS Number	2170801-87-1
IUPAC name	benzyl (2S)-2-(8-aminoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Molecular formula	C₁₈H₁₉N₅O₂
Molecular weight	337.4 g/mol
Exact mass	337.1539
Grade	Reference Standard
HSN code	38229090
InChIKey	WJIKKVMDANXFJV-AWEZNQCLSA-N
SMILES	C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C3=NC=C4N3C=CN=C4N
PubChem CID	164063965

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 5
TPSA	85.8 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Benzyl?

The CAS Registry Number of Benzyl is 2170801-87-1. It is also known as benzyl (2S)-2-{8-aminoimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate, (S)-3-(1-Cbz-2-pyrrolidinyl)imidazo[1,5-a]pyrazin-8-amine, Phenylmethyl (2S)-2-(8-aminoimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate.

What is the molecular formula and molecular weight of Benzyl?

Benzyl has the molecular formula C18H19N5O2 and a molecular weight of 337.4 g/mol. Its IUPAC name is benzyl (2S)-2-(8-aminoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate.

What is Benzyl used for?

Benzyl is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Benzyl can I order?

We supply Benzyl in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Benzyl?

Yes. Every lot of Benzyl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Benzyl be shipped internationally?

Yes. Benzyl is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.