6-Dehydrocortisol Acetate

About 6-Dehydrocortisol Acetate

6-Dehydrocortisol Acetate is an impurity of Hydrocortisone carrying the CAS registry number 21940-45-4. Formula C23H30O6, molecular weight 402.5 g/mol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Hydrocortisone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Dehydrocortisol Acetate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Dehydrocortisol Acetate
Catalogue No.	VQ-022809
CAS Number	21940-45-4
IUPAC name	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formula	C₂₃H₃₀O₆
Molecular weight	402.5 g/mol
Exact mass	402.2042
Grade	Reference Standard
HSN code	38229090
InChIKey	VXLNNRNWOGKRPL-JZYPGELDSA-N
SMILES	CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2C=CC4=CC(=O)CC[C@]34C)O)C)O
PubChem CID	18594072

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 6
TPSA	101 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Dehydrocortisol Acetate?

The CAS Registry Number of 6-Dehydrocortisol Acetate is 21940-45-4. It is also known as 11beta,17,21-Trihydroxypregna-4,6-diene-3,20-dione 21-Acetate.

What is the molecular formula and molecular weight of 6-Dehydrocortisol Acetate?

6-Dehydrocortisol Acetate has the molecular formula C23H30O6 and a molecular weight of 402.5 g/mol. Its IUPAC name is [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate.

What is 6-Dehydrocortisol Acetate used for?

6-Dehydrocortisol Acetate is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Dehydrocortisol Acetate can I order?

We supply 6-Dehydrocortisol Acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Dehydrocortisol Acetate?

Yes. Every lot of 6-Dehydrocortisol Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Dehydrocortisol Acetate be shipped internationally?

Yes. 6-Dehydrocortisol Acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.