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VAQORAOlanzapine EP Impurity B
Synonyms: 2-Methyl-5,10-dihydro-4H-benzo[b]thieno[2,3-e][1,4]diazepin-4-one · 2-methyl-5,10-dihydro-4h-thieno[2,3-b][1,5]benzodiazepin-4-one · 2-Methyl-5,10-dihydro-4H-thieno(2,3-b)(1,5)benzodiazepin-4-one · 4H-Thieno(2,3-b)(1,5)benzodiazepin-4-one, 5,10-dihydro-2-methyl-
CAS No.221176-49-4
FormulaC12H10N2OS
Mol. weight230.29
Catalogue No.VQ-006553
PurityReference Standard
HSN38229090
Olanzapine EP Impurity B (CAS 221176-49-4) – Olanzapine impurity standard. C12H10N2OS, MW 230.29. Request a quote: COA, bulk packs and worldwide export.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Olanzapine EP Impurity B
Listed under CAS 221176-49-4, Olanzapine EP Impurity B is a pharmacopeial impurity of Olanzapine available from Vaqora Chemicals. With the molecular formula C12H10N2OS, it has a molar mass of 230.29 g/mol. Its systematic (IUPAC) name is 2-methyl-5,10-dihydrothieno[3,2-c][1,5]benzodiazepin-4-one. It is also known as Olanzapine specified impurity B or Olanzapine-lactam.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.
Pharmaceutical QC and development laboratories use this impurity standard of Olanzapine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Olanzapine EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.
Typical applications
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Industries
Related to Olanzapine
View every impurity, metabolite and intermediate we list for Olanzapine.
Olanzapine impuritiesGrade guides
Specifications & identifiers
| Product name | Olanzapine EP Impurity B |
|---|---|
| Catalogue No. | VQ-006553 |
| CAS Number | 221176-49-4 |
| IUPAC name | 2-methyl-5,10-dihydrothieno[3,2-c][1,5]benzodiazepin-4-one |
| Molecular formula | C12H10N2OS |
| Molecular weight | 230.29 g/mol |
| Exact mass | 230.0514 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | LVTDAJJOMLNXFS-UHFFFAOYSA-N |
| SMILES | CC1=CC2=C(S1)NC3=CC=CC=C3NC2=O |
| PubChem CID | 29978685 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.8 |
| H-bond donors / acceptors | 2 / 3 |
| TPSA | 69.4 Ų |
| Synonyms | 2-Methyl-5,10-dihydro-4H-benzo[b]thieno[2,3-e][1,4]diazepin-4-one, 2-methyl-5,10-dihydro-4h-thieno[2,3-b][1,5]benzodiazepin-4-one, 2-Methyl-5,10-dihydro-4H-thieno(2,3-b)(1,5)benzodiazepin-4-one, 4H-Thieno(2,3-b)(1,5)benzodiazepin-4-one, 5,10-dihydro-2-methyl-, Olanzapine specified impurity B, Olanzapine-lactam, 5,10-Dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-4-one, 5,10-Dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-4-one(Olanzapine Impurity), 2-Methyl-4,9-dihydro-3-thia-4,9-diazabenzo[f]azulene-10-one, Olanzapine Lactam, 2-Methyl-5,10-dihydro-4H-thieno[2,3-b][1,5]benzodiazepin-4-one (Olanzapine Lactame), Olanzapine-related Compound B |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H335May cause respiratory irritation
Precautionary statements: P261, P271, P304 + P340, P319, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Olanzapine EP Impurity B?
The CAS Registry Number of Olanzapine EP Impurity B is 221176-49-4. It is also known as 2-Methyl-5,10-dihydro-4H-benzo[b]thieno[2,3-e][1,4]diazepin-4-one, 2-methyl-5,10-dihydro-4h-thieno[2,3-b][1,5]benzodiazepin-4-one, 2-Methyl-5,10-dihydro-4H-thieno(2,3-b)(1,5)benzodiazepin-4-one.
What is the molecular formula and molecular weight of Olanzapine EP Impurity B?
Olanzapine EP Impurity B has the molecular formula C12H10N2OS and a molecular weight of 230.29 g/mol. Its IUPAC name is 2-methyl-5,10-dihydrothieno[3,2-c][1,5]benzodiazepin-4-one.
What is Olanzapine EP Impurity B used for?
Olanzapine EP Impurity B is supplied as a characterised reference material related to Olanzapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Olanzapine EP Impurity B can I order?
We supply Olanzapine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Olanzapine EP Impurity B?
Yes. Every lot of Olanzapine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Olanzapine EP Impurity B be shipped internationally?
Yes. Olanzapine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Olanzapine EP Impurity B
We reply within one business day with price, pack options, lead time and documentation.
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