Diclofenac EP Impurity B

Name: Diclofenac EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022367

About Diclofenac EP Impurity B

Diclofenac EP Impurity B (CAS 22121-58-0) is a pharmacopeial impurity of Diclofenac offered by Vaqora Chemicals. With the molecular formula C13H9Cl2NO, it has a molar mass of 266.12 g/mol. Its systematic (IUPAC) name is 2-(2,6-dichloroanilino)benzaldehyde. Common synonyms include Diclofenac Sodium - Impurity B and Diclofenac Impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Diclofenac to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Diclofenac EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diclofenac

View every impurity, metabolite and intermediate we list for Diclofenac.

Diclofenac impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diclofenac EP Impurity B
Catalogue No.	VQ-022367
CAS Number	22121-58-0
IUPAC name	2-(2,6-dichloroanilino)benzaldehyde
Molecular formula	C₁₃H₉Cl₂NO
Molecular weight	266.12 g/mol
Exact mass	265.0061
Grade	Reference Standard
HSN code	38229090
InChIKey	MILOIOYXRHLAAH-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C=O)NC2=C(C=CC=C2Cl)Cl
PubChem CID	12906536

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	1 / 2
TPSA	29.1 Å²
Synonyms	Diclofenac Sodium - Impurity B, Diclofenac Impurity B, Diclofenac Aldehyde, 2-((2,6-Dichlorophenyl)amino)benzaldehyde, o-(2,6-Dichloroanilino)benzaldehyde, Anthranilaldehyde, N-(2,6-dichlorophenyl)-, Benzaldehyde, 2-((2,6-dichlorophenyl)amino)-, Benzaldehyde, 2-[(2,6-dichlorophenyl)amino]-, Diclofenac Sodium impurity B, Diclofenac potassium impurity B, Diclofenac sodium specified impurity B, Diclofenac potassium specified impurity B

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diclofenac EP Impurity B?

The CAS Registry Number of Diclofenac EP Impurity B is 22121-58-0. It is also known as Diclofenac Sodium - Impurity B, Diclofenac Impurity B, Diclofenac Aldehyde.

What is the molecular formula and molecular weight of Diclofenac EP Impurity B?

Diclofenac EP Impurity B has the molecular formula C13H9Cl2NO and a molecular weight of 266.12 g/mol. Its IUPAC name is 2-(2,6-dichloroanilino)benzaldehyde.

What is Diclofenac EP Impurity B used for?

Diclofenac EP Impurity B is supplied as a characterised reference material related to Diclofenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diclofenac EP Impurity B can I order?

We supply Diclofenac EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diclofenac EP Impurity B?

Yes. Every lot of Diclofenac EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diclofenac EP Impurity B be shipped internationally?

Yes. Diclofenac EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.