Cholecalciferol EP Impurity D

About Cholecalciferol EP Impurity D

Cholecalciferol EP Impurity D is a pharmacopeial impurity of Cholecalciferol carrying the CAS registry number 22350-43-2. With the molecular formula C27H44O, it has a molar mass of 384.6 g/mol. It is also known as Isotachysterol 3 or Cholecalciferol - Impurity D.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Cholecalciferol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cholecalciferol EP Impurity D is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cholecalciferol

View every impurity, metabolite and intermediate we list for Cholecalciferol.

Cholecalciferol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cholecalciferol EP Impurity D
Catalogue No.	VQ-021144
CAS Number	22350-43-2
IUPAC name	(1S)-3-[(E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,5,6,7-hexahydroinden-4-yl]ethenyl]-4-methylcyclohex-3-en-1-ol
Molecular formula	C₂₇H₄₄O
Molecular weight	384.6 g/mol
Exact mass	384.3392
Grade	Reference Standard
HSN code	38229090
InChIKey	ZPZNWLRQHDLNNV-QVEMQNNUSA-N
SMILES	CC1=C(C[C@H](CC1)O)/C=C/C2=C3CC[C@@H]([C@]3(CCC2)C)[C@H](C)CCCC(C)C
PubChem CID	5283714

Physical properties
Physical form	Solid
LogP (XLogP3)	7.4
H-bond donors / acceptors	1 / 1
TPSA	20.2 Å²
Synonyms	Cholecalciferol EP Impurity D / iso-tachysterol-3, Isotachysterol 3, Cholecalciferol - Impurity D, isotachysterol3, Cholecalciferol impurity D, (6E)-(3S)-9,10-seco-5(10),6,8(14)-cholestatrien-3-ol, 9,10-Secocholesta-5(10),6,8(14)-trien-3beta-ol, (E)-, 9,10-Secocholesta-5(10),6,8(14)-trien-3-ol, (3beta,6E)-

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P318, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cholecalciferol EP Impurity D?

The CAS Registry Number of Cholecalciferol EP Impurity D is 22350-43-2. It is also known as Cholecalciferol EP Impurity D / iso-tachysterol-3, Isotachysterol 3, Cholecalciferol - Impurity D.

What is the molecular formula and molecular weight of Cholecalciferol EP Impurity D?

Cholecalciferol EP Impurity D has the molecular formula C27H44O and a molecular weight of 384.6 g/mol. Its IUPAC name is (1S)-3-[(E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-1,2,3,5,6,7-hexahydroinden-4-yl]ethenyl]-4-methylcyclohex-3-en-1-ol.

What is Cholecalciferol EP Impurity D used for?

Cholecalciferol EP Impurity D is supplied as a characterised reference material related to Cholecalciferol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cholecalciferol EP Impurity D can I order?

We supply Cholecalciferol EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cholecalciferol EP Impurity D?

Yes. Every lot of Cholecalciferol EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cholecalciferol EP Impurity D be shipped internationally?

Yes. Cholecalciferol EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.