N-Nitroso Valsartan (Rotamers)

About N-Nitroso Valsartan (Rotamers)

N-Nitroso Valsartan (Rotamers) is a nitrosamine impurity of Valsartan carrying the CAS registry number 2254485-68-0 at a purity of 60%. With the molecular formula C19H20N6O3, it has a molar mass of 380.4 g/mol. Its systematic (IUPAC) name is (2S)-3-methyl-2-[nitroso-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid. Common synonyms include N-Nitroso Valsartan.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso Valsartan (Rotamers) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Valsartan (Rotamers)
Catalogue No.	VQ-006964
CAS Number	2254485-68-0
IUPAC name	(2S)-3-methyl-2-[nitroso-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
Molecular formula	C₁₉H₂₀N₆O₃
Molecular weight	380.4 g/mol
Exact mass	380.1597
Grade	Reference Standard
Purity / assay	60%
HSN code	38229090
InChIKey	QRFFNLYLXKQEDK-KRWDZBQOSA-N
SMILES	CC(C)[C@@H](C(=O)O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)N=O
PubChem CID	146297898

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	2 / 8
TPSA	124 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Valsartan (Rotamers)?

The CAS Registry Number of N-Nitroso Valsartan (Rotamers) is 2254485-68-0. It is also known as N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-nitroso-L-valine, N-Nitroso Valsartan.

What is the molecular formula and molecular weight of N-Nitroso Valsartan (Rotamers)?

N-Nitroso Valsartan (Rotamers) has the molecular formula C19H20N6O3 and a molecular weight of 380.4 g/mol. Its IUPAC name is (2S)-3-methyl-2-[nitroso-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid.

What is N-Nitroso Valsartan (Rotamers) used for?

N-Nitroso Valsartan (Rotamers) is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Valsartan (Rotamers) can I order?

We supply N-Nitroso Valsartan (Rotamers) in Reference Standard (60%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Valsartan (Rotamers)?

Yes. Every lot of N-Nitroso Valsartan (Rotamers) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Valsartan (Rotamers) be shipped internationally?

Yes. We export N-Nitroso Valsartan (Rotamers) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.