Ibrutinib Nitroso Impurity 1

Name: Ibrutinib Nitroso Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-006839

About Ibrutinib Nitroso Impurity 1

Listed under CAS 2256059-43-3, Ibrutinib Nitroso Impurity 1 is a nitrosamine impurity of Ibrutinib available from Vaqora Chemicals. Its molecular formula is C22H21N7O2 and its molecular weight is 415.4 g/mol. Its systematic (IUPAC) name is 1-(1-nitrosopiperidin-3-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ibrutinib Nitroso Impurity 1 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ibrutinib Nitroso Impurity 1
Catalogue No.	VQ-006839
CAS Number	2256059-43-3
IUPAC name	1-(1-nitrosopiperidin-3-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
Molecular formula	C₂₂H₂₁N₇O₂
Molecular weight	415.4 g/mol
Exact mass	415.1757
Grade	Reference Standard
HSN code	38229090
InChIKey	NKMYLWJBFJCTHG-UHFFFAOYSA-N
SMILES	C1CC(CN(C1)N=O)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
PubChem CID	146519151

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	1 / 8
TPSA	112 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ibrutinib Nitroso Impurity 1?

The CAS Registry Number of Ibrutinib Nitroso Impurity 1 is 2256059-43-3. It is also known as 1-(1-Nitroso-3-piperidinyl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine.

What is the molecular formula and molecular weight of Ibrutinib Nitroso Impurity 1?

Ibrutinib Nitroso Impurity 1 has the molecular formula C22H21N7O2 and a molecular weight of 415.4 g/mol. Its IUPAC name is 1-(1-nitrosopiperidin-3-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine.

What is Ibrutinib Nitroso Impurity 1 used for?

Ibrutinib Nitroso Impurity 1 is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ibrutinib Nitroso Impurity 1 can I order?

We supply Ibrutinib Nitroso Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ibrutinib Nitroso Impurity 1?

Yes. Every lot of Ibrutinib Nitroso Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ibrutinib Nitroso Impurity 1 be shipped internationally?

Yes. We export Ibrutinib Nitroso Impurity 1 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.