Acebutolol EP Impurity B

Name: Acebutolol EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-024125

About Acebutolol EP Impurity B

Vaqora Chemicals supplies Acebutolol EP Impurity B, a pharmacopeial impurity of Acebutolol registered under CAS number 22568-64-5. Its molecular formula is C16H24N2O4 and its molecular weight is 308.37 g/mol. Systematically, it is named N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide. Alternative names: Rac Diacetolol and Acebutolol EP Impurity B (Free Base).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Acebutolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Acebutolol EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Acebutolol

View every impurity, metabolite and intermediate we list for Acebutolol.

Acebutolol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Acebutolol EP Impurity B
Catalogue No.	VQ-024125
CAS Number	22568-64-5
IUPAC name	N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
Molecular formula	C₁₆H₂₄N₂O₄
Molecular weight	308.37 g/mol
Exact mass	308.1736
Grade	Reference Standard
HSN code	38229090
InChIKey	AWOGXJOBNAWQSF-UHFFFAOYSA-N
SMILES	CC(C)NCC(COC1=C(C=C(C=C1)NC(=O)C)C(=O)C)O
PubChem CID	50894

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 5
TPSA	87.7 Å²
Synonyms	Rac Diacetolol, Acebutolol EP Impurity B (Free Base), Acebutolol Hydrochloride - Impurity B (Freebase), Diacetolol, Acetamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-, Acetyl acebutolol, RS-1-(4-acetamido-2-acetylphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride, (+/-)-Diacetolol, N-(3-Acetyl-4-(2-hydroxy-3-(isopropylamino)-propoxy)phenyl)acetamide, Acetylacebutolol, N-(3-acetyl-4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, (1)-N-(3-Acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acebutolol EP Impurity B?

The CAS Registry Number of Acebutolol EP Impurity B is 22568-64-5. It is also known as Rac Diacetolol, Acebutolol EP Impurity B (Free Base), Acebutolol Hydrochloride - Impurity B (Freebase).

What is the molecular formula and molecular weight of Acebutolol EP Impurity B?

Acebutolol EP Impurity B has the molecular formula C16H24N2O4 and a molecular weight of 308.37 g/mol. Its IUPAC name is N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide.

What is Acebutolol EP Impurity B used for?

Acebutolol EP Impurity B is supplied as a characterised reference material related to Acebutolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acebutolol EP Impurity B can I order?

We supply Acebutolol EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acebutolol EP Impurity B?

Yes. Every lot of Acebutolol EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acebutolol EP Impurity B be shipped internationally?

Yes. Acebutolol EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.