Sacubitril (2R,4R) Isomer

Name: Sacubitril (2R,4R) Isomer
Brand: Vaqora Chemicals
SKU: VQ-005852

About Sacubitril (2R,4R) Isomer

Sacubitril (2R,4R) Isomer is an impurity of Sacubitril carrying the CAS registry number 2259708-00-2 with a typical assay of 91.71%. With the molecular formula C24H29NO5, it has a molar mass of 411.5 g/mol. Its systematic (IUPAC) name is 4-[[(2R,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid. Common synonyms include 2R,4R-Sacubitril and (2R,4R)-Sacubitril.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Sacubitril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sacubitril (2R,4R) Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril (2R,4R) Isomer
Catalogue No.	VQ-005852
CAS Number	2259708-00-2
Other CAS	766480-48-2, 3081732-59-1
IUPAC name	4-[[(2R,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid
Molecular formula	C₂₄H₂₉NO₅
Molecular weight	411.5 g/mol
Exact mass	411.2046
Grade	Reference Standard
Purity / assay	91.71%
HSN code	38229090
InChIKey	PYNXFZCZUAOOQC-DYESRHJHSA-N
SMILES	CCOC(=O)[C@H](C)C[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O
PubChem CID	9829628

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 5
TPSA	92.7 Å²
Synonyms	4-Ethyl (αR,γR)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, Sacubitril (2R,4R) Isomer, 2R,4R-Sacubitril, (2R,4R)-Sacubitril, Sacubitril-(2R,4R)-Isomer, pound Ca pound(c), Sacubitril, (2R,4R)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril (2R,4R) Isomer?

The CAS Registry Number of Sacubitril (2R,4R) Isomer is 2259708-00-2. It is also known as 4-Ethyl (αR,γR)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, Sacubitril (2R,4R) Isomer, 2R,4R-Sacubitril.

What is the molecular formula and molecular weight of Sacubitril (2R,4R) Isomer?

Sacubitril (2R,4R) Isomer has the molecular formula C24H29NO5 and a molecular weight of 411.5 g/mol. Its IUPAC name is 4-[[(2R,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid.

What is Sacubitril (2R,4R) Isomer used for?

Sacubitril (2R,4R) Isomer is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril (2R,4R) Isomer can I order?

We supply Sacubitril (2R,4R) Isomer in Reference Standard (91.71%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril (2R,4R) Isomer?

Yes. Every lot of Sacubitril (2R,4R) Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril (2R,4R) Isomer be shipped internationally?

Yes. We export Sacubitril (2R,4R) Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.