Metolazone EP Impurity E

About Metolazone EP Impurity E

Metolazone EP Impurity E is a pharmacopeial impurity of Metolazone carrying the CAS registry number 23380-54-3. Its molecular formula is C14H14ClN3O3S and its molecular weight is 339.8 g/mol. Its systematic (IUPAC) name is 2-amino-4-chloro-N-(2-methylphenyl)-5-sulfamoylbenzamide. Alternative names: Metolazone benzamide analog and Metolazone - Impurity E.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Metolazone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Metolazone EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Metolazone

View every impurity, metabolite and intermediate we list for Metolazone.

Metolazone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Metolazone EP Impurity E
Catalogue No.	VQ-023113
CAS Number	23380-54-3
IUPAC name	2-amino-4-chloro-N-(2-methylphenyl)-5-sulfamoylbenzamide
Molecular formula	C₁₄H₁₄ClN₃O₃S
Molecular weight	339.8 g/mol
Exact mass	339.0444
Grade	Reference Standard
HSN code	38229090
InChIKey	YWXVGSRRJLYMHX-UHFFFAOYSA-N
SMILES	CC1=CC=CC=C1NC(=O)C2=CC(=C(C=C2N)Cl)S(=O)(=O)N
PubChem CID	90079

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 5
TPSA	124 Å²
Synonyms	Metolazone benzamide analog, Metolazone - Impurity E, 2-Amino-4-chloro-5-sulfamoyl-N-(o-tolyl)benzamide, 2-Amino-5-(aminosulfonyl)-4-chloro-N-(2-methylphenyl)benzamide, 2-Amino-5-(aminosulphonyl)-4-chloro-N-(o-tolyl)benzamide, Benzamide, 2-amino-5-(aminosulfonyl)-4-chloro-N-(2-methylphenyl)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metolazone EP Impurity E?

The CAS Registry Number of Metolazone EP Impurity E is 23380-54-3. It is also known as Metolazone benzamide analog, Metolazone - Impurity E, 2-Amino-4-chloro-5-sulfamoyl-N-(o-tolyl)benzamide.

What is the molecular formula and molecular weight of Metolazone EP Impurity E?

Metolazone EP Impurity E has the molecular formula C14H14ClN3O3S and a molecular weight of 339.8 g/mol. Its IUPAC name is 2-amino-4-chloro-N-(2-methylphenyl)-5-sulfamoylbenzamide.

What is Metolazone EP Impurity E used for?

Metolazone EP Impurity E is supplied as a characterised reference material related to Metolazone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metolazone EP Impurity E can I order?

We supply Metolazone EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metolazone EP Impurity E?

Yes. Every lot of Metolazone EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metolazone EP Impurity E be shipped internationally?

Yes. We export Metolazone EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.