Sacubitril Diethyl Ester

Name: Sacubitril Diethyl Ester
Brand: Vaqora Chemicals
SKU: VQ-013786

About Sacubitril Diethyl Ester

Sacubitril Diethyl Ester (CAS 2376611-98-0) is a process intermediate or related compound of Sacubitril offered by Vaqora Chemicals at a purity of 98%. The compound has the formula C26H33NO5, corresponding to a molecular weight of 439.5 g/mol. Its systematic (IUPAC) name is ethyl (2R,4S)-4-[(4-ethoxy-4-oxobutanoyl)amino]-2-methyl-5-(4-phenylphenyl)pentanoate. It is also known as AHU 377 ethyl ester.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Sacubitril, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Sacubitril Diethyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril Diethyl Ester
Catalogue No.	VQ-013786
CAS Number	2376611-98-0
IUPAC name	ethyl (2R,4S)-4-[(4-ethoxy-4-oxobutanoyl)amino]-2-methyl-5-(4-phenylphenyl)pentanoate
Molecular formula	C₂₆H₃₃NO₅
Molecular weight	439.5 g/mol
Exact mass	439.2359
Grade	Reference Standard
Purity / assay	98%
HSN code	2933
InChIKey	GFXSVOAZSQONQY-XXBNENTESA-N
SMILES	CCOC(=O)CCC(=O)N[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)C[C@@H](C)C(=O)OCC
PubChem CID	121332375

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	1 / 5
TPSA	81.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril Diethyl Ester?

The CAS Registry Number of Sacubitril Diethyl Ester is 2376611-98-0. It is also known as (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate, Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate, Ethyl (αR,γS)-γ-[(4-ethoxy-1,4-dioxobutyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate.

What is the molecular formula and molecular weight of Sacubitril Diethyl Ester?

Sacubitril Diethyl Ester has the molecular formula C26H33NO5 and a molecular weight of 439.5 g/mol. Its IUPAC name is ethyl (2R,4S)-4-[(4-ethoxy-4-oxobutanoyl)amino]-2-methyl-5-(4-phenylphenyl)pentanoate.

What is Sacubitril Diethyl Ester used for?

Sacubitril Diethyl Ester is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril Diethyl Ester can I order?

We supply Sacubitril Diethyl Ester in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril Diethyl Ester?

Yes. Every lot of Sacubitril Diethyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril Diethyl Ester be shipped internationally?

Yes. We export Sacubitril Diethyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.