Propofol EP Impurity E

Name: Propofol EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-006608

About Propofol EP Impurity E

Listed under CAS 2416-95-7, Propofol EP Impurity E is a pharmacopeial impurity of Propofol available from Vaqora Chemicals. Formula C24H34O2, molecular weight 354.5 g/mol. Its systematic (IUPAC) name is 4-[4-hydroxy-3,5-di(propan-2-yl)phenyl]-2,6-di(propan-2-yl)phenol. Common synonyms include Propofol Dimer and 2,2',6,6'-Tetraisopropyl-p,p'-biphenol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Propofol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Propofol EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Propofol

View every impurity, metabolite and intermediate we list for Propofol.

Propofol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Propofol EP Impurity E
Catalogue No.	VQ-006608
CAS Number	2416-95-7
IUPAC name	4-[4-hydroxy-3,5-di(propan-2-yl)phenyl]-2,6-di(propan-2-yl)phenol
Molecular formula	C₂₄H₃₄O₂
Molecular weight	354.5 g/mol
Exact mass	354.2559
Grade	Reference Standard
HSN code	38229090
InChIKey	QAISRHCMPQROAX-UHFFFAOYSA-N
SMILES	CC(C)C1=CC(=CC(=C1O)C(C)C)C2=CC(=C(C(=C2)C(C)C)O)C(C)C
PubChem CID	11602828

Physical properties
Physical form	Solid
LogP (XLogP3)	7.3
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	3,3',5,5'-Tetrakis(1-methylethyl)-[1,1'-biphenyl]-4,4'-diol, 3,3',5,5'-Tetrakis(1- methylethyl)biphenyl-4,4'-diol, Propofol Dimer, 2,2',6,6'-Tetraisopropyl-p,p'-biphenol, 3,3',5,5'-Tetraisopropyl-4,4'-dihydroxybiphenyl, 3,3'-5,5'-Tetraisopropyldiphenol, Propofol Related Compound A (USP), Dipropofol, 3,3',5,5'-Tetrakis(1-methylethyl)biphenyl-4,4'-diol, (1,1'-Biphenyl)-4,4'-diol, 3,3',5,5'-tetrakis(1-methylethyl)-, [1,1'-Biphenyl]-4,4'-diol, 3,3',5,5'-tetrakis(1-methylethyl)-, Propofol specified impurity E

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Propofol EP Impurity E?

The CAS Registry Number of Propofol EP Impurity E is 2416-95-7. It is also known as 3,3',5,5'-Tetrakis(1-methylethyl)-[1,1'-biphenyl]-4,4'-diol, 3,3',5,5'-Tetrakis(1- methylethyl)biphenyl-4,4'-diol, Propofol Dimer.

What is the molecular formula and molecular weight of Propofol EP Impurity E?

Propofol EP Impurity E has the molecular formula C24H34O2 and a molecular weight of 354.5 g/mol. Its IUPAC name is 4-[4-hydroxy-3,5-di(propan-2-yl)phenyl]-2,6-di(propan-2-yl)phenol.

What is Propofol EP Impurity E used for?

Propofol EP Impurity E is supplied as a characterised reference material related to Propofol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Propofol EP Impurity E can I order?

We supply Propofol EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Propofol EP Impurity E?

Yes. Every lot of Propofol EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Propofol EP Impurity E be shipped internationally?

Yes. Propofol EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.