4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile 244768-32-9

Name: 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile
Brand: Vaqora Chemicals
SKU: VQ-021331

About 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile

Listed under CAS 244768-32-9, 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is an impurity of Rilpivirine available from Vaqora Chemicals. The compound has the formula C11H7ClN4, corresponding to a molecular weight of 230.65 g/mol. Systematically, it is named 4-[(4-chloropyrimidin-2-yl)amino]benzonitrile. Alternative names: 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile and 4-(4-chloropyrimidin-2-ylamino)benzonitrile.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Rilpivirine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rilpivirine

View every impurity, metabolite and intermediate we list for Rilpivirine.

Rilpivirine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile
Catalogue No.	VQ-021331
CAS Number	244768-32-9
IUPAC name	4-[(4-chloropyrimidin-2-yl)amino]benzonitrile
Molecular formula	C₁₁H₇ClN₄
Molecular weight	230.65 g/mol
Exact mass	230.0359
Grade	Reference Standard
HSN code	38229090
InChIKey	QXCHAADSAYQDHL-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C#N)NC2=NC=CC(=N2)Cl
PubChem CID	11195595

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 4
TPSA	61.6 Å²
Synonyms	4-[(4-Chloropyrimidin-2-yl)amino]-Benzonitrile, 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile, Benzonitrile, 4-[(4-chloro-2-pyrimidinyl)amino]-, 4-(4-chloropyrimidin-2-ylamino)benzonitrile, 4-(4-chloro-pyrimidin-2-ylamino)benzonitrile, 4-(4-chloropyrimidin-2-ylamino)-benzonitrile, 4-(4-Chloro-pyrimidin-2-ylamino)-benzonitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile?

The CAS Registry Number of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is 244768-32-9. It is also known as 4-[(4-Chloropyrimidin-2-yl)amino]-Benzonitrile, 4-((4-Chloropyrimidin-2-yl)amino)benzonitrile, Benzonitrile, 4-[(4-chloro-2-pyrimidinyl)amino]-.

What is the molecular formula and molecular weight of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile?

4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile has the molecular formula C11H7ClN4 and a molecular weight of 230.65 g/mol. Its IUPAC name is 4-[(4-chloropyrimidin-2-yl)amino]benzonitrile.

What is 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile used for?

4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is supplied as a characterised reference material related to Rilpivirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile can I order?

We supply 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile?

Yes. Every lot of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile be shipped internationally?

Yes. 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.