Quetiapine EP Impurity R

Name: Quetiapine EP Impurity R
Brand: Vaqora Chemicals
SKU: VQ-027696

About Quetiapine EP Impurity R

Quetiapine EP Impurity R (CAS 2459-05-4) is a pharmacopeial impurity of Quetiapine offered by Vaqora Chemicals. Its molecular formula is C6H8O4 and its molecular weight is 144.12 g/mol. Its systematic (IUPAC) name is (E)-4-ethoxy-4-oxobut-2-enoic acid. Alternative names: Monoethyl Fumarate and Fumaric Acid Monoethyl Ester.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Quetiapine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Quetiapine EP Impurity R
Catalogue No.	VQ-027696
CAS Number	2459-05-4
IUPAC name	(E)-4-ethoxy-4-oxobut-2-enoic acid
Molecular formula	C₆H₈O₄
Molecular weight	144.12 g/mol
Exact mass	144.0423
Grade	Reference Standard
HSN code	38229090
InChIKey	XLYMOEINVGRTEX-ONEGZZNKSA-N
SMILES	CCOC(=O)/C=C/C(=O)O
PubChem CID	5358902

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 4
TPSA	63.6 Å²
Synonyms	Monoethyl Fumarate, Fumaric Acid Monoethyl Ester, Quetiapine - Impurity R, Ethyl fumarate, Fumaric acid, monoethyl ester, 2-Butenedioic acid (E)-, monoethyl ester, ethylhydrogenfumarate, mono-Ethyl fumarate, Ethyl hydrogen fumarate, (2E)-4-ethoxy-4-oxobut-2-enoic acid, 2-Butenedioic acid (2E)-, 1-ethyl ester, (2E)-3-(ethoxycarbonyl)prop-2-enoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Quetiapine EP Impurity R?

The CAS Registry Number of Quetiapine EP Impurity R is 2459-05-4. It is also known as Monoethyl Fumarate, Fumaric Acid Monoethyl Ester, Quetiapine - Impurity R.

What is the molecular formula and molecular weight of Quetiapine EP Impurity R?

Quetiapine EP Impurity R has the molecular formula C6H8O4 and a molecular weight of 144.12 g/mol. Its IUPAC name is (E)-4-ethoxy-4-oxobut-2-enoic acid.

What is Quetiapine EP Impurity R used for?

Quetiapine EP Impurity R is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Quetiapine EP Impurity R can I order?

We supply Quetiapine EP Impurity R in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Quetiapine EP Impurity R?

Yes. Every lot of Quetiapine EP Impurity R is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Quetiapine EP Impurity R be shipped internationally?

Yes. Quetiapine EP Impurity R is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.