Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer… 2475188-05-5

About Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl

Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl is a metabolite or degradation product of Aprepitant carrying the CAS registry number 2475188-05-5. With the molecular formula C20H19ClF7NO2, it has a molar mass of 473.8 g/mol. It is also known as Aprepitant Impurity 18 or Aprepitant Impurity E.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Aprepitant, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl
Catalogue No.	VQ-035779
CAS Number	2475188-05-5
IUPAC name	(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine;hydrochloride
Molecular formula	C₂₀H₁₉ClF₇NO₂
Molecular weight	473.8 g/mol
Exact mass	473.0993
Grade	Reference Standard
HSN code	38229090
InChIKey	DWCCMKXSGCKMJF-QCJXVUQZSA-N
SMILES	C[C@@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@H]2[C@H](NCCO2)C3=CC=C(C=C3)F.Cl
PubChem CID	129011674

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 10
TPSA	30.5 Å²
Synonyms	Aprepitant M2 Metabolite (1S,2S,3R)-Isomer Hydrochloride, Aprepitant Impurity 18, Aprepitant Impurity E, Aprepitant Impurity 11, Aprepitant Impurity N2 HCl

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl?

The CAS Registry Number of Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl is 2475188-05-5. It is also known as Aprepitant M2 Metabolite (1S,2S,3R)-Isomer Hydrochloride, Aprepitant Impurity 18, Aprepitant Impurity E.

What is the molecular formula and molecular weight of Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl?

Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl has the molecular formula C20H19ClF7NO2 and a molecular weight of 473.8 g/mol.

What is Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl used for?

Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl can I order?

We supply Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl?

Yes. Every lot of Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl be shipped internationally?

Yes. We export Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.