Nintedanib 4-Nitrophenyl 2-(4-Nitroso)
Synonyms: N-Methyl-N-(4-nitrophenyl)-4-nitroso-1-piperazineacetamide · N-methyl-N-(4-nitrophenyl)-4-nitroso
Nintedanib 4-Nitrophenyl 2-(4-Nitroso) (CAS 2490403-92-2) – nitrosamine impurity reference standard, 98%. C13H17N5O4, MW 307.31. With COA, ships worldwide.
About Nintedanib 4-Nitrophenyl 2-(4-Nitroso)
Listed under CAS 2490403-92-2, Nintedanib 4-Nitrophenyl 2-(4-Nitroso) is a nitrosamine impurity of Nintedanib available from Vaqora Chemicals, specified at 98% purity. Its molecular formula is C13H17N5O4 and its molecular weight is 307.31 g/mol. Systematically, it is named N-methyl-N-(4-nitrophenyl)-2-(4-nitrosopiperazin-1-yl)acetamide. It is also known as N-methyl-N-(4-nitrophenyl)-4-nitroso.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies Nintedanib 4-Nitrophenyl 2-(4-Nitroso) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- Nitrosamine risk assessment
- Trace LC-MS/MS quantitation
- Method validation (AMV)
- Regulatory submissions
Industries
View every impurity, metabolite and intermediate we list for Nintedanib.
Nintedanib impuritiesSpecifications & identifiers
| Product name | Nintedanib 4-Nitrophenyl 2-(4-Nitroso) |
|---|---|
| Catalogue No. | VQ-007008 |
| CAS Number | 2490403-92-2 |
| IUPAC name | N-methyl-N-(4-nitrophenyl)-2-(4-nitrosopiperazin-1-yl)acetamide |
| Molecular formula | C13H17N5O4 |
| Molecular weight | 307.31 g/mol |
| Exact mass | 307.1281 |
| Grade | Reference Standard |
| Purity / assay | 98% |
| HSN code | 38229090 |
| InChIKey | BXTDJRYUGBIVDM-UHFFFAOYSA-N |
| SMILES | CN(C1=CC=C(C=C1)[N+](=O)[O-])C(=O)CN2CCN(CC2)N=O |
| PubChem CID | 155820971 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.9 |
| H-bond donors / acceptors | 0 / 7 |
| TPSA | 102 Ų |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH351Suspected of causing cancer
Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Nintedanib 4-Nitrophenyl 2-(4-Nitroso)?
The CAS Registry Number of Nintedanib 4-Nitrophenyl 2-(4-Nitroso) is 2490403-92-2. It is also known as N-Methyl-N-(4-nitrophenyl)-4-nitroso-1-piperazineacetamide, N-methyl-N-(4-nitrophenyl)-4-nitroso.
What is the molecular formula and molecular weight of Nintedanib 4-Nitrophenyl 2-(4-Nitroso)?
Nintedanib 4-Nitrophenyl 2-(4-Nitroso) has the molecular formula C13H17N5O4 and a molecular weight of 307.31 g/mol. Its IUPAC name is N-methyl-N-(4-nitrophenyl)-2-(4-nitrosopiperazin-1-yl)acetamide.
What is Nintedanib 4-Nitrophenyl 2-(4-Nitroso) used for?
Nintedanib 4-Nitrophenyl 2-(4-Nitroso) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Nintedanib 4-Nitrophenyl 2-(4-Nitroso) can I order?
We supply Nintedanib 4-Nitrophenyl 2-(4-Nitroso) in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Nintedanib 4-Nitrophenyl 2-(4-Nitroso)?
Yes. Every lot of Nintedanib 4-Nitrophenyl 2-(4-Nitroso) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Nintedanib 4-Nitrophenyl 2-(4-Nitroso) be shipped internationally?
Yes. Nintedanib 4-Nitrophenyl 2-(4-Nitroso) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Nintedanib 4-Nitrophenyl 2-(4-Nitroso)
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