Dexamethasone EP Impurity D

Name: Dexamethasone EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-006320

About Dexamethasone EP Impurity D

Vaqora Chemicals supplies Dexamethasone EP Impurity D, a pharmacopeial impurity of Dexamethasone registered under CAS number 24916-90-3, specified at 95.02% purity. The compound has the formula C22H28O5, corresponding to a molecular weight of 372.5 g/mol. Alternative names: Mometasone EP Impurity L and Dexamethasone 9,11-Epoxide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Dexamethasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Dexamethasone EP Impurity D in 10 mg, 25 mg and 50 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dexamethasone EP Impurity D
Catalogue No.	VQ-006320
CAS Number	24916-90-3
IUPAC name	(1S,2S,10S,11S,13R,14R,15S,17S)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one
Molecular formula	C₂₂H₂₈O₅
Molecular weight	372.5 g/mol
Exact mass	372.1937
Grade	Reference Standard
Purity / assay	95.02%
HSN code	38229090
InChIKey	GBDXNHBVYAMODG-QDBZYVRYSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]35[C@@H](O5)C[C@@]2([C@]1(C(=O)CO)O)C)C
PubChem CID	11143226

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 5
TPSA	87.1 Å²
Synonyms	Mometasone EP Impurity L, (9β,11β,16α)-9,11-Epoxy-17,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione, 17,21-Dihydroxy-16α-methyl-9β,11β-epoxypregna-1,4-diene-3,20-dione, 9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione, Dexamethasone 9,11-Epoxide, Dexamethasone EP Impurity D / Mometasone EP Impurity L, 9beta,11beta-Epoxy-17,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, (9b,11b,16a)-9,11-Epoxy-17,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione, 8DM, 8DM/16, A-methyl epoxide, 9,11beta-Epoxy-17,21-dihydroxy-16alpha-methyl-9beta-pregna-1,4-diene-3,20-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dexamethasone EP Impurity D?

The CAS Registry Number of Dexamethasone EP Impurity D is 24916-90-3. It is also known as Mometasone EP Impurity L, (9β,11β,16α)-9,11-Epoxy-17,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione, 17,21-Dihydroxy-16α-methyl-9β,11β-epoxypregna-1,4-diene-3,20-dione.

What is the molecular formula and molecular weight of Dexamethasone EP Impurity D?

Dexamethasone EP Impurity D has the molecular formula C22H28O5 and a molecular weight of 372.5 g/mol. Its IUPAC name is (1S,2S,10S,11S,13R,14R,15S,17S)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one.

What is Dexamethasone EP Impurity D used for?

Dexamethasone EP Impurity D is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dexamethasone EP Impurity D can I order?

We supply Dexamethasone EP Impurity D in Reference Standard (95.02%) grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dexamethasone EP Impurity D?

Yes. Every lot of Dexamethasone EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dexamethasone EP Impurity D be shipped internationally?

Yes. Dexamethasone EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.