Darunavir DNVRC-4

About Darunavir DNVRC-4

Darunavir DNVRC-4 is an impurity of Darunavir carrying the CAS registry number 251105-80-3. Formula C20H27N3O5S, molecular weight 421.5 g/mol. Systematically, it is named N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-4-nitrobenzenesulfonamide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Darunavir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Darunavir DNVRC-4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Darunavir

View every impurity, metabolite and intermediate we list for Darunavir.

Darunavir impurities

Specifications & identifiers

Chemical identifiers
Product name	Darunavir DNVRC-4
Catalogue No.	VQ-047958
CAS Number	251105-80-3
IUPAC name	N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-4-nitrobenzenesulfonamide
Molecular formula	C₂₀H₂₇N₃O₅S
Molecular weight	421.5 g/mol
Exact mass	421.1671
Grade	Reference Standard
HSN code	38229090
InChIKey	BPRSPRGTVGSTKD-VQTJNVASSA-N
SMILES	CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)N)O)S(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]
PubChem CID	10112927

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 7
TPSA	138 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Darunavir DNVRC-4?

The CAS Registry Number of Darunavir DNVRC-4 is 251105-80-3. It is also known as N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide, N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-(2-methylpropyl)-4-nitrobenzenesulfonamide, Benzenesulfonamide,N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-4-nitro-.

What is the molecular formula and molecular weight of Darunavir DNVRC-4?

Darunavir DNVRC-4 has the molecular formula C20H27N3O5S and a molecular weight of 421.5 g/mol. Its IUPAC name is N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-4-nitrobenzenesulfonamide.

What is Darunavir DNVRC-4 used for?

Darunavir DNVRC-4 is supplied as a characterised reference material related to Darunavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Darunavir DNVRC-4 can I order?

We supply Darunavir DNVRC-4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Darunavir DNVRC-4?

Yes. Every lot of Darunavir DNVRC-4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Darunavir DNVRC-4 be shipped internationally?

Yes. We export Darunavir DNVRC-4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.