Levothyroxine Sodium Hydrate

Name: Levothyroxine Sodium Hydrate
Brand: Vaqora Chemicals
SKU: VQ-043211

About Levothyroxine Sodium Hydrate

Levothyroxine Sodium Hydrate (CAS 25416-65-3) is a high-purity reference standard of Levothyroxine offered by Vaqora Chemicals. Formula C15H12I4NNaO5, molecular weight 816.87 g/mol. It is also known as Levothyroxine sodium monohydrate or L-Thyroxine sodium xhydrate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Levothyroxine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Levothyroxine Sodium Hydrate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine Sodium Hydrate
Catalogue No.	VQ-043211
CAS Number	25416-65-3
IUPAC name	sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
Molecular formula	C₁₅H₁₂I₄NNaO₅
Molecular weight	816.87 g/mol
Exact mass	816.6792
Grade	Reference Standard
HSN code	38229090
InChIKey	ANMYAHDLKVNJJO-LTCKWSDVSA-M
SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.O.[Na+]
PubChem CID	23667619

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 6
TPSA	96.6 Å²
Synonyms	Levothyroxine sodium monohydrate, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, monohydrate, L-Thyroxine sodium xhydrate, L-Thyroxine sodium hydrate, Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate xhydrate, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate, Levoroxin, Tivoral, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Sodium Salt Hydrate, Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate hydrate, Levo-Tiroxina Glaxo, L-thyroxine sodium salt monohydrate

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine Sodium Hydrate?

The CAS Registry Number of Levothyroxine Sodium Hydrate is 25416-65-3. It is also known as Levothyroxine sodium monohydrate, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, monohydrate, L-Thyroxine sodium xhydrate.

What is the molecular formula and molecular weight of Levothyroxine Sodium Hydrate?

Levothyroxine Sodium Hydrate has the molecular formula C15H12I4NNaO5 and a molecular weight of 816.87 g/mol.

What is Levothyroxine Sodium Hydrate used for?

Levothyroxine Sodium Hydrate is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine Sodium Hydrate can I order?

We supply Levothyroxine Sodium Hydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine Sodium Hydrate?

Yes. Every lot of Levothyroxine Sodium Hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine Sodium Hydrate be shipped internationally?

Yes. Levothyroxine Sodium Hydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.