2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-di… 2607-52-5

About 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one

2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one is a process intermediate or related compound of Everolimus carrying the CAS registry number 2607-52-5. The compound has the formula C15H22O, corresponding to a molecular weight of 218.33 g/mol. Systematically, it is named 2,6-ditert-butyl-4-methylidenecyclohexa-2,5-dien-1-one. Common synonyms include Bht-quinone methide and Bht-QM.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Everolimus, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Everolimus

View every impurity, metabolite and intermediate we list for Everolimus.

Everolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one
Catalogue No.	VQ-012897
CAS Number	2607-52-5
IUPAC name	2,6-ditert-butyl-4-methylidenecyclohexa-2,5-dien-1-one
Molecular formula	C₁₅H₂₂O
Molecular weight	218.33 g/mol
Exact mass	218.1671
Grade	Reference Standard
InChIKey	JJQCWPWUHZFKBN-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=C)C=C(C1=O)C(C)(C)C
PubChem CID	107736

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²
Synonyms	2,6-Bis(1,1-dimethylethyl)-4-methylene-2,5-cyclohexadien-1-one, 2,6-Di(tert-butyl)-4-methylene-2,5-cyclohexadiene-1-one, 2,6-Di-tert-butyl-4-methylene-2,5-cyclohexadienone, 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one, Bht-quinone methide, Bht-QM, 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone, 2,5-Ccyclohexadien-1-one, 2,6-bis(1,1-dimethylethyl)-4-methylene-, 2,6-di-tert-butyl-4-methylenecyclohexa-2,5-dienone, 2,5-Cyclohexadien-1-one, 2,6-bis(1,1-dimethylethyl)-4-methylene-, 2,6-di-t-Butyl-4-methylene-2,5-cyclohexadiene-1-one, 2,6-ditert-butyl-4-methylene-cyclohexa-2,5-dien-1-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one?

The CAS Registry Number of 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one is 2607-52-5. It is also known as 2,6-Bis(1,1-dimethylethyl)-4-methylene-2,5-cyclohexadien-1-one, 2,6-Di(tert-butyl)-4-methylene-2,5-cyclohexadiene-1-one, 2,6-Di-tert-butyl-4-methylene-2,5-cyclohexadienone.

What is the molecular formula and molecular weight of 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one?

2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one has the molecular formula C15H22O and a molecular weight of 218.33 g/mol. Its IUPAC name is 2,6-ditert-butyl-4-methylidenecyclohexa-2,5-dien-1-one.

What is 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one used for?

2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one is supplied as a characterised reference material related to Everolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one can I order?

We supply 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one?

Yes. Every lot of 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one be shipped internationally?

Yes. We export 2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.