Duloxetine EP Impurity F (Hydrochloride)

Name: Duloxetine EP Impurity F (Hydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-006348

About Duloxetine EP Impurity F (Hydrochloride)

Listed under CAS 2748376-86-3, Duloxetine EP Impurity F (Hydrochloride) is a pharmacopeial impurity of Duloxetine available from Vaqora Chemicals at a purity of 98.42%. The compound has the formula C18H20ClNOS, corresponding to a molecular weight of 333.9 g/mol. Systematically, it is named (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-3-ylpropan-1-amine. Hydrochloride. Common synonyms include Duloxetine EP Impurity F HCl.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Duloxetine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Duloxetine EP Impurity F (Hydrochloride)
Catalogue No.	VQ-006348
CAS Number	2748376-86-3
Other CAS	959392-22-4
IUPAC name	(3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-3-ylpropan-1-amine;hydrochloride
Molecular formula	C₁₈H₂₀ClNOS
Molecular weight	333.9 g/mol
Exact mass	333.0954
Grade	Reference Standard
Purity / assay	98.42%
HSN code	38229090
InChIKey	OXTVVINBECSMHI-LMOVPXPDSA-N
SMILES	CNCC[C@@H](C1=CSC=C1)OC2=CC=CC3=CC=CC=C32.Cl
PubChem CID	163203193

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	49.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Duloxetine EP Impurity F (Hydrochloride)?

The CAS Registry Number of Duloxetine EP Impurity F (Hydrochloride) is 2748376-86-3. It is also known as (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride, Duloxetine USP Related Compound F (Hydrochloride), Duloxetine EP Impurity F HCl.

What is the molecular formula and molecular weight of Duloxetine EP Impurity F (Hydrochloride)?

Duloxetine EP Impurity F (Hydrochloride) has the molecular formula C18H20ClNOS and a molecular weight of 333.9 g/mol.

What is Duloxetine EP Impurity F (Hydrochloride) used for?

Duloxetine EP Impurity F (Hydrochloride) is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Duloxetine EP Impurity F (Hydrochloride) can I order?

We supply Duloxetine EP Impurity F (Hydrochloride) in Reference Standard (98.42%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Duloxetine EP Impurity F (Hydrochloride)?

Yes. Every lot of Duloxetine EP Impurity F (Hydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Duloxetine EP Impurity F (Hydrochloride) be shipped internationally?

Yes. Duloxetine EP Impurity F (Hydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.