10-Formyl-7,8-dihydro Folic Acid

Name: 10-Formyl-7,8-dihydro Folic Acid
Brand: Vaqora Chemicals
SKU: VQ-028863

About 10-Formyl-7,8-dihydro Folic Acid

Listed under CAS 28459-40-7, 10-Formyl-7,8-dihydro Folic Acid is an impurity of Levofolinate available from Vaqora Chemicals. Formula C20H21N7O7, molecular weight 471.4 g/mol. Systematically, it is named (2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid. It is also known as 10-Formyldihydrofolate or 10-formyldihydrofolic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Levofolinate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 10-Formyl-7,8-dihydro Folic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Levofolinate

View every impurity, metabolite and intermediate we list for Levofolinate.

Levofolinate impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Formyl-7,8-dihydro Folic Acid
Catalogue No.	VQ-028863
CAS Number	28459-40-7
IUPAC name	(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₀H₂₁N₇O₇
Molecular weight	471.4 g/mol
Exact mass	471.1502
Grade	Reference Standard
HSN code	38229090
InChIKey	UXFQDXABPXWSTK-ZDUSSCGKSA-N
SMILES	C1C(=NC2=C(N1)N=C(NC2=O)N)CN(C=O)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	135398690

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	6 / 10
TPSA	216 Å²
Synonyms	10-Formyldihydrofolate, 10-formyldihydrofolic acid, F-D folic acid, 10-formyl-7,8-dihydrofolate, N-(10-formyl-7,8-dihydropteroyl)-L-glutamate, 28459-40-7 free acid

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Formyl-7,8-dihydro Folic Acid?

The CAS Registry Number of 10-Formyl-7,8-dihydro Folic Acid is 28459-40-7. It is also known as 10-Formyldihydrofolate, 10-formyldihydrofolic acid, F-D folic acid.

What is the molecular formula and molecular weight of 10-Formyl-7,8-dihydro Folic Acid?

10-Formyl-7,8-dihydro Folic Acid has the molecular formula C20H21N7O7 and a molecular weight of 471.4 g/mol. Its IUPAC name is (2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid.

What is 10-Formyl-7,8-dihydro Folic Acid used for?

10-Formyl-7,8-dihydro Folic Acid is supplied as a characterised reference material related to Levofolinate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Formyl-7,8-dihydro Folic Acid can I order?

We supply 10-Formyl-7,8-dihydro Folic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Formyl-7,8-dihydro Folic Acid?

Yes. Every lot of 10-Formyl-7,8-dihydro Folic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Formyl-7,8-dihydro Folic Acid be shipped internationally?

Yes. 10-Formyl-7,8-dihydro Folic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.