Metolazone EP Impurity B

Name: Metolazone EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023115

About Metolazone EP Impurity B

Metolazone EP Impurity B (CAS 28508-63-6) is a pharmacopeial impurity of Metolazone offered by Vaqora Chemicals. Its molecular formula is C16H16ClN3O3S and its molecular weight is 365.8 g/mol. Systematically, it is named 7-chloro-2-methyl-3-(4-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide. Common synonyms include para-Metolazone and Metolazone - Impurity B.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Metolazone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Metolazone EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Metolazone

View every impurity, metabolite and intermediate we list for Metolazone.

Metolazone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Metolazone EP Impurity B
Catalogue No.	VQ-023115
CAS Number	28508-63-6
IUPAC name	7-chloro-2-methyl-3-(4-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
Molecular formula	C₁₆H₁₆ClN₃O₃S
Molecular weight	365.8 g/mol
Exact mass	365.0601
Grade	Reference Standard
HSN code	38229090
InChIKey	OZRXBEQHWXLTOR-UHFFFAOYSA-N
SMILES	CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=C(C=C3)C)S(=O)(=O)N)Cl
PubChem CID	71737791

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	2 / 5
TPSA	101 Å²
Synonyms	para-Metolazone, Metolazone - Impurity B, p-Metolazone, 4'-Metolazone, (+/-)-Para-metolazone, 2'-Desmethyl-4'-methylmetolazone, 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(4-methylphenyl)-4-oxo-, N-Des(o-tolyl)-N-(p-tolyl) Metolazone, Metolazone Impurity D, 7-Chloro-2-methyl-4-oxo-3-(p-tolyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metolazone EP Impurity B?

The CAS Registry Number of Metolazone EP Impurity B is 28508-63-6. It is also known as para-Metolazone, Metolazone - Impurity B, p-Metolazone.

What is the molecular formula and molecular weight of Metolazone EP Impurity B?

Metolazone EP Impurity B has the molecular formula C16H16ClN3O3S and a molecular weight of 365.8 g/mol. Its IUPAC name is 7-chloro-2-methyl-3-(4-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide.

What is Metolazone EP Impurity B used for?

Metolazone EP Impurity B is supplied as a characterised reference material related to Metolazone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metolazone EP Impurity B can I order?

We supply Metolazone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metolazone EP Impurity B?

Yes. Every lot of Metolazone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metolazone EP Impurity B be shipped internationally?

Yes. We export Metolazone EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.