Sodium Estrone-d4 Sulfate

About Sodium Estrone-d4 Sulfate

Sodium Estrone-d4 Sulfate is a stable isotope labelled analogue related to Estrone carrying the CAS registry number 285979-80-8. The compound has the formula C18H21NaO5S, corresponding to a molecular weight of 376.4 g/mol. It is also known as Sodium Estrone-2,4,16,16-d4 Sulfate or Estrone sulfate-d4 (sodium).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Estrone

View every impurity, metabolite and intermediate we list for Estrone.

Estrone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sodium Estrone-d4 Sulfate
Catalogue No.	VQ-037136
CAS Number	285979-80-8
IUPAC name	sodium [(8R,9S,13S,14S)-2,4,16,16-tetradeuterio-13-methyl-17-oxo-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-yl] sulfate
Molecular formula	C₁₈H₂₁NaO₅S
Molecular weight	376.4 g/mol
Exact mass	376.1258
Grade	Reference Standard
HSN code	38229090
InChIKey	VUCAHVBMSFIGAI-IGBMKMNFSA-M
SMILES	[2H]C1=CC2=C(CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC(C4=O)([2H])[2H])C)C(=C1OS(=O)(=O)[O-])[2H].[Na+]
PubChem CID	71311484

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 5
TPSA	91.9 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sodium Estrone-d4 Sulfate?

The CAS Registry Number of Sodium Estrone-d4 Sulfate is 285979-80-8. It is also known as Sodium Estrone-2,4,16,16-d4 Sulfate, Sodium 17-oxo(2,4,16,16-~2~H_4_)estra-1,3,5(10)-trien-3-yl sulfate, Estrone sulfate-d4 (sodium).

What is the molecular formula and molecular weight of Sodium Estrone-d4 Sulfate?

Sodium Estrone-d4 Sulfate has the molecular formula C18H21NaO5S and a molecular weight of 376.4 g/mol. Its IUPAC name is sodium [(8R,9S,13S,14S)-2,4,16,16-tetradeuterio-13-methyl-17-oxo-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-yl] sulfate.

What is Sodium Estrone-d4 Sulfate used for?

Sodium Estrone-d4 Sulfate is supplied as a characterised reference material related to Estrone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sodium Estrone-d4 Sulfate can I order?

We supply Sodium Estrone-d4 Sulfate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sodium Estrone-d4 Sulfate?

Yes. Every lot of Sodium Estrone-d4 Sulfate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sodium Estrone-d4 Sulfate be shipped internationally?

Yes. Sodium Estrone-d4 Sulfate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.