Zidovudine EP Impurity J

About Zidovudine EP Impurity J

Zidovudine EP Impurity J is a pharmacopeial impurity of Zidovudine carrying the CAS registry number 29706-84-1. Its molecular formula is C29H27N5O4 and its molecular weight is 509.6 g/mol. Its systematic (IUPAC) name is 1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione. Common synonyms include Zidovudine - Impurity J and 3'-Azido-3'-deoxy-5'-O-tritylthymidine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Zidovudine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Zidovudine EP Impurity J is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Zidovudine

View every impurity, metabolite and intermediate we list for Zidovudine.

Zidovudine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Zidovudine EP Impurity J
Catalogue No.	VQ-024049
CAS Number	29706-84-1
IUPAC name	1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Molecular formula	C₂₉H₂₇N₅O₄
Molecular weight	509.6 g/mol
Exact mass	509.2063
Grade	Reference Standard
HSN code	38229090
InChIKey	AZPSSDWPMSICSH-JIMJEQGWSA-N
SMILES	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)N=[N+]=[N-]
PubChem CID	10929300

Physical properties
Physical form	Solid
LogP (XLogP3)	5.3
H-bond donors / acceptors	1 / 6
TPSA	82.2 Å²
Synonyms	Zidovudine - Impurity J, 3'-Azido-3'-deoxy-5'-O-tritylthymidine, 3'-Azido-3'-deoxy-5'-O-(triphenylmethyl)thymidine, Thymidine, 3'-azido-3'-deoxy-5'-O-(triphenylmethyl)-, Thymidine, 3'-azido-3'-deoxy-5'-o-trityl-, Zidovudine impurity J, Zidovudine Impurity 2, 5'-O-Trt-Zidovudine, 3'-Azido-3'-deoxy-5'-O-triphenylmethyl thymidine, 3'-Azido-3'-deoxy-5'-O-triphenylMethylthyMidine

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H312Harmful in contact with skin
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P280, P302 + P352, P317, P321, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Zidovudine EP Impurity J?

The CAS Registry Number of Zidovudine EP Impurity J is 29706-84-1. It is also known as Zidovudine - Impurity J, 3'-Azido-3'-deoxy-5'-O-tritylthymidine, 3'-Azido-3'-deoxy-5'-O-(triphenylmethyl)thymidine.

What is the molecular formula and molecular weight of Zidovudine EP Impurity J?

Zidovudine EP Impurity J has the molecular formula C29H27N5O4 and a molecular weight of 509.6 g/mol. Its IUPAC name is 1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.

What is Zidovudine EP Impurity J used for?

Zidovudine EP Impurity J is supplied as a characterised reference material related to Zidovudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Zidovudine EP Impurity J can I order?

We supply Zidovudine EP Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Zidovudine EP Impurity J?

Yes. Every lot of Zidovudine EP Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Zidovudine EP Impurity J be shipped internationally?

Yes. Zidovudine EP Impurity J is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.