Trimethoprim EP Impurity I

Name: Trimethoprim EP Impurity I
Brand: Vaqora Chemicals
SKU: VQ-028538

About Trimethoprim EP Impurity I

Listed under CAS 30078-48-9, Trimethoprim EP Impurity I is a pharmacopeial impurity of Trimethoprim available from Vaqora Chemicals. With the molecular formula C19H20N2O3, it has a molar mass of 324.4 g/mol. Its systematic (IUPAC) name is (Z)-3-anilino-2-[(3,4,5-trimethoxyphenyl)methyl]prop-2-enenitrile. Common synonyms include Trimethoprim - Impurity I.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Trimethoprim, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimethoprim EP Impurity I
Catalogue No.	VQ-028538
CAS Number	30078-48-9
IUPAC name	(Z)-3-anilino-2-[(3,4,5-trimethoxyphenyl)methyl]prop-2-enenitrile
Molecular formula	C₁₉H₂₀N₂O₃
Molecular weight	324.4 g/mol
Exact mass	324.1474
Grade	Reference Standard
HSN code	38229090
InChIKey	LMGNGGBSQVPQCO-SQFISAMPSA-N
SMILES	COC1=CC(=CC(=C1OC)OC)C/C(=C/NC2=CC=CC=C2)/C#N
PubChem CID	3035337

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 5
TPSA	63.5 Å²
Synonyms	Trimethoprim EP Impurity I(Mixture of cis/trans Isomers), Trimethoprim - Impurity I, 3-Anilino-2-(3,4,5,-trimethoxybenzyl)acrylonitrile, 3-(phenylamino)-2-(3,4,5-trimethoxybenzyl)prop-2-enenitrile, 3-Anilino-2-(3,4,5,-trimethoxybenzyl)acrylonitrile, (Z)-, 3-(Phenylamino)-2-(3,4,5-trimethoxybenzyl)acrylonitrile, (Z)-3-(Phenylamino)-2-(3,4,5-trimethoxybenzyl)acrylonitrile, 3-(phenylamino)-2-(3,4,5-trimethoxybenzyl)prop-2enenitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimethoprim EP Impurity I?

The CAS Registry Number of Trimethoprim EP Impurity I is 30078-48-9. It is also known as Trimethoprim EP Impurity I(Mixture of cis/trans Isomers), Trimethoprim - Impurity I, 3-Anilino-2-(3,4,5,-trimethoxybenzyl)acrylonitrile.

What is the molecular formula and molecular weight of Trimethoprim EP Impurity I?

Trimethoprim EP Impurity I has the molecular formula C19H20N2O3 and a molecular weight of 324.4 g/mol. Its IUPAC name is (Z)-3-anilino-2-[(3,4,5-trimethoxyphenyl)methyl]prop-2-enenitrile.

What is Trimethoprim EP Impurity I used for?

Trimethoprim EP Impurity I is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimethoprim EP Impurity I can I order?

We supply Trimethoprim EP Impurity I in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimethoprim EP Impurity I?

Yes. Every lot of Trimethoprim EP Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimethoprim EP Impurity I be shipped internationally?

Yes. Trimethoprim EP Impurity I is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.