Trimethoprim EP Impurity B

Name: Trimethoprim EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-028543

About Trimethoprim EP Impurity B

Trimethoprim EP Impurity B (CAS 30806-86-1) is a pharmacopeial impurity of Trimethoprim offered by Vaqora Chemicals. The compound has the formula C14H16N4O4, corresponding to a molecular weight of 304.3 g/mol. Systematically, it is named (2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanone. Common synonyms include Trimethoprim - Impurity B and Trimethoprim Keto Analogue.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Trimethoprim to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Trimethoprim EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimethoprim EP Impurity B
Catalogue No.	VQ-028543
CAS Number	30806-86-1
IUPAC name	(2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanone
Molecular formula	C₁₄H₁₆N₄O₄
Molecular weight	304.3 g/mol
Exact mass	304.1172
Grade	Reference Standard
HSN code	38229090
InChIKey	GAAPPIKAFNZRLA-UHFFFAOYSA-N
SMILES	COC1=CC(=CC(=C1OC)OC)C(=O)C2=CN=C(N=C2N)N
PubChem CID	13734023

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 8
TPSA	123 Å²
Synonyms	Trimethoprim - Impurity B, Trimethoprim Keto Analogue, 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, (2,4-Diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone, Keto trimethoprim, Methanone, (2,4-diamino-5-pyrimidinyl)(3,4,5-trimethoxyphenyl)-, Trimethoprim Impurity B, 2,4-diamino-5-(3,4,5-trimethoxybenzoyl)pyrimidine

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed

Precautionary statements: P203, P264, P270, P280, P301 + P316, P301 + P317, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimethoprim EP Impurity B?

The CAS Registry Number of Trimethoprim EP Impurity B is 30806-86-1. It is also known as Trimethoprim - Impurity B, Trimethoprim Keto Analogue, 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine.

What is the molecular formula and molecular weight of Trimethoprim EP Impurity B?

Trimethoprim EP Impurity B has the molecular formula C14H16N4O4 and a molecular weight of 304.3 g/mol. Its IUPAC name is (2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanone.

What is Trimethoprim EP Impurity B used for?

Trimethoprim EP Impurity B is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimethoprim EP Impurity B can I order?

We supply Trimethoprim EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimethoprim EP Impurity B?

Yes. Every lot of Trimethoprim EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimethoprim EP Impurity B be shipped internationally?

Yes. Trimethoprim EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.