Iohexol EP Impurity A

About Iohexol EP Impurity A

Iohexol EP Impurity A is a pharmacopeial impurity of Iohexol carrying the CAS registry number 31127-80-7. With the molecular formula C16H20I3N3O7, it has a molar mass of 747.06 g/mol. Its systematic (IUPAC) name is 5-acetamido-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide. It is also known as Iodixanol EP Impurity B or Iohexol - Impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Iohexol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Iohexol

View every impurity, metabolite and intermediate we list for Iohexol.

Iohexol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Iohexol EP Impurity A
Catalogue No.	VQ-026173
CAS Number	31127-80-7
IUPAC name	5-acetamido-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
Molecular formula	C₁₆H₂₀I₃N₃O₇
Molecular weight	747.06 g/mol
Exact mass	746.8435
Grade	Reference Standard
HSN code	38229090
InChIKey	BHCBLTRDEYPMFZ-UHFFFAOYSA-N
SMILES	CC(=O)NC1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
PubChem CID	11115326

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.3
H-bond donors / acceptors	7 / 7
TPSA	168 Å²
Synonyms	Iodixanol EP Impurity B, Iohexol - Impurity A, 5-Acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, 5-(Acetylamino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide, 5-Acetamido-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide, Iomeprol hydrolysate-1, 5-acetylamino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, 5-(Acetylamino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, Isophthalamide, 5-acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-, (+/-)-5-(Acetylamino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide, 1,3-Benzenedicarboxamide, 5-(acetylamino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Iohexol EP Impurity A?

The CAS Registry Number of Iohexol EP Impurity A is 31127-80-7. It is also known as Iodixanol EP Impurity B, Iohexol - Impurity A, 5-Acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide.

What is the molecular formula and molecular weight of Iohexol EP Impurity A?

Iohexol EP Impurity A has the molecular formula C16H20I3N3O7 and a molecular weight of 747.06 g/mol. Its IUPAC name is 5-acetamido-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide.

What is Iohexol EP Impurity A used for?

Iohexol EP Impurity A is supplied as a characterised reference material related to Iohexol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Iohexol EP Impurity A can I order?

We supply Iohexol EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Iohexol EP Impurity A?

Yes. Every lot of Iohexol EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Iohexol EP Impurity A be shipped internationally?

Yes. We export Iohexol EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.