Axitinib WS

Name: Axitinib WS
Brand: Vaqora Chemicals
SKU: VQ-007327

About Axitinib WS

Vaqora Chemicals supplies Axitinib WS, a high-purity reference standard of Axitinib registered under CAS number 319460-85-0. With the molecular formula C22H18N4OS, it has a molar mass of 386.5 g/mol. Systematically, it is named N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide. Alternative names: Axitinib and Inlyta.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Axitinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Axitinib WS in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Axitinib

View every impurity, metabolite and intermediate we list for Axitinib.

Axitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Axitinib WS
Catalogue No.	VQ-007327
CAS Number	319460-85-0
IUPAC name	N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
Molecular formula	C₂₂H₁₈N₄OS
Molecular weight	386.5 g/mol
Exact mass	386.1201
Grade	Reference Standard
HSN code	38229090
InChIKey	RITAVMQDGBJQJZ-FMIVXFBMSA-N
SMILES	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4
PubChem CID	6450551

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 4
TPSA	96 Å²
Synonyms	N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide, (N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide), Axitinib, Inlyta, N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide, N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide, Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)-, N-methyl-2-({3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide, Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-, N-methyl-2-((3-((E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide, (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide, N-methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P317, P318, P319, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Axitinib WS?

The CAS Registry Number of Axitinib WS is 319460-85-0. It is also known as N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide, (N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide), Axitinib.

What is the molecular formula and molecular weight of Axitinib WS?

Axitinib WS has the molecular formula C22H18N4OS and a molecular weight of 386.5 g/mol. Its IUPAC name is N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide.

What is Axitinib WS used for?

Axitinib WS is supplied as a characterised reference material related to Axitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Axitinib WS can I order?

We supply Axitinib WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Axitinib WS?

Yes. Every lot of Axitinib WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Axitinib WS be shipped internationally?

Yes. Axitinib WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.