6-Epidoxycycline

Name: 6-Epidoxycycline
Brand: Vaqora Chemicals
SKU: VQ-022443

About 6-Epidoxycycline

Vaqora Chemicals supplies 6-Epidoxycycline, an impurity of Doxycycline registered under CAS number 3219-99-6. With the molecular formula C22H24N2O8, it has a molar mass of 444.4 g/mol. It is also known as epi-Doxycycline or 6-Epioxytetracycline, 6-deoxy-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Doxycycline, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Doxycycline

View every impurity, metabolite and intermediate we list for Doxycycline.

Doxycycline impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Epidoxycycline
Catalogue No.	VQ-022443
CAS Number	3219-99-6
IUPAC name	(4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
Molecular formula	C₂₂H₂₄N₂O₈
Molecular weight	444.4 g/mol
Exact mass	444.1533
Grade	Reference Standard
HSN code	38229090
InChIKey	SGKRLCUYIXIAHR-IPJAVASBSA-N
SMILES	C[C@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
PubChem CID	54685534

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	6 / 9
TPSA	182 Å²
Synonyms	epi-Doxycycline, 6-Epioxytetracycline, 6-deoxy-, 6-epi-Oxytetracycline, 6-deoxy-, beta-6-Deoxy-5-hydroxytetracycline, 3219-99-6(free base), Discontinued-Replaced by E585925

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Epidoxycycline?

The CAS Registry Number of 6-Epidoxycycline is 3219-99-6. It is also known as epi-Doxycycline, 6-Epioxytetracycline, 6-deoxy-, 6-epi-Oxytetracycline, 6-deoxy-.

What is the molecular formula and molecular weight of 6-Epidoxycycline?

6-Epidoxycycline has the molecular formula C22H24N2O8 and a molecular weight of 444.4 g/mol. Its IUPAC name is (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide.

What is 6-Epidoxycycline used for?

6-Epidoxycycline is supplied as a characterised reference material related to Doxycycline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Epidoxycycline can I order?

We supply 6-Epidoxycycline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Epidoxycycline?

Yes. Every lot of 6-Epidoxycycline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Epidoxycycline be shipped internationally?

Yes. 6-Epidoxycycline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.