Docetaxel EP Impurity E

Name: Docetaxel EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022415

About Docetaxel EP Impurity E

Docetaxel EP Impurity E (CAS 32981-86-5) is a pharmacopeial impurity of Docetaxel offered by Vaqora Chemicals. Its molecular formula is C29H36O10 and its molecular weight is 544.6 g/mol. Common synonyms include 10-Deacetyl Baccatin III and 10-Deacetylbaccatin III.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 10 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Docetaxel to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Docetaxel EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Docetaxel

View every impurity, metabolite and intermediate we list for Docetaxel.

Docetaxel impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Docetaxel EP Impurity E
Catalogue No.	VQ-022415
CAS Number	32981-86-5
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12,15-tetrahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₂₉H₃₆O₁₀
Molecular weight	544.6 g/mol
Exact mass	544.2308
Grade	Reference Standard
HSN code	38229090
InChIKey	YWLXLRUDGLRYDR-ZHPRIASZSA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O
PubChem CID	154272

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	4 / 10
TPSA	160 Å²
Synonyms	10-Deacetyl Baccatin III, 10-Deacetylbaccatin III, Docetaxel - Impurity E, Cabazitaxel - Impurity L, 10-Deacetylbaccatine III, 10-DB III, 10-Deacetyl-baccatine III, 10-Deacetylbaccatin, zoate, 10-O-Deacetylbaccatin III, 10-DAB, 10-DeacetylbaccatinIII

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Docetaxel EP Impurity E?

The CAS Registry Number of Docetaxel EP Impurity E is 32981-86-5. It is also known as 10-Deacetyl Baccatin III, 10-Deacetylbaccatin III, Docetaxel - Impurity E.

What is the molecular formula and molecular weight of Docetaxel EP Impurity E?

Docetaxel EP Impurity E has the molecular formula C29H36O10 and a molecular weight of 544.6 g/mol.

What is Docetaxel EP Impurity E used for?

Docetaxel EP Impurity E is supplied as a characterised reference material related to Docetaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Docetaxel EP Impurity E can I order?

We supply Docetaxel EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Docetaxel EP Impurity E?

Yes. Every lot of Docetaxel EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Docetaxel EP Impurity E be shipped internationally?

Yes. Docetaxel EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.