2-Hydroxy Estrone

Name: 2-Hydroxy Estrone
Brand: Vaqora Chemicals
SKU: VQ-037095

About 2-Hydroxy Estrone

Vaqora Chemicals supplies 2-Hydroxy Estrone, a metabolite or degradation product of Estriol registered under CAS number 362-06-1. The compound has the formula C18H22O3, corresponding to a molecular weight of 286.4 g/mol. The IUPAC name is (8R,9S,13S,14S)-2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one. Alternative names: Catecholestrone and 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Estriol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Hydroxy Estrone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Estriol

View every impurity, metabolite and intermediate we list for Estriol.

Estriol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy Estrone
Catalogue No.	VQ-037095
CAS Number	362-06-1
IUPAC name	(8R,9S,13S,14S)-2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Molecular formula	C₁₈H₂₂O₃
Molecular weight	286.4 g/mol
Exact mass	286.1569
Grade	Reference Standard
HSN code	38229090
InChIKey	SWINWPBPEKHUOD-JPVZDGGYSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=CC(=C(C=C34)O)O
PubChem CID	440623

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	Catecholestrone, 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one, 2-OHE1, 2,3-dihydroxy-estra-1,3,5(10)-trien-17-one, Estra-1,3,5(1)-trien-17-one, 2,3-dihydroxy-, Estra-1,3,5(10-trien-17-one, 2,3-dihydroxy)-, 2-OHE(1), 1,3,5(10)-Estratrien-2,3-diol-17-one, Estra-1,3,5(10)-trien-17-one, 2,3-dihydroxy-

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy Estrone?

The CAS Registry Number of 2-Hydroxy Estrone is 362-06-1. It is also known as Catecholestrone, 2,3-Dihydroxyestra-1,3,5(10)-trien-17-one, 2-OHE1.

What is the molecular formula and molecular weight of 2-Hydroxy Estrone?

2-Hydroxy Estrone has the molecular formula C18H22O3 and a molecular weight of 286.4 g/mol. Its IUPAC name is (8R,9S,13S,14S)-2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one.

What is 2-Hydroxy Estrone used for?

2-Hydroxy Estrone is supplied as a characterised reference material related to Estriol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy Estrone can I order?

We supply 2-Hydroxy Estrone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy Estrone?

Yes. Every lot of 2-Hydroxy Estrone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy Estrone be shipped internationally?

Yes. 2-Hydroxy Estrone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.