Dimethyl

About Dimethyl

Dimethyl is an impurity of Pralatrexate carrying the CAS registry number 374777-77-2. Formula C25H27N7O5, molecular weight 505.5 g/mol. Systematically, it is named dimethyl (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioate. Common synonyms include PLQS-6 and CS-M1821.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Pralatrexate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dimethyl is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pralatrexate

View every impurity, metabolite and intermediate we list for Pralatrexate.

Pralatrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	Dimethyl
Catalogue No.	VQ-041576
CAS Number	374777-77-2
IUPAC name	dimethyl (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioate
Molecular formula	C₂₅H₂₇N₇O₅
Molecular weight	505.5 g/mol
Exact mass	505.2074
Grade	Reference Standard
HSN code	38229090
InChIKey	APABDPCMDMRBDJ-DAFXYXGESA-N
SMILES	COC(=O)CC[C@@H](C(=O)OC)NC(=O)C1=CC=C(C=C1)C(CC#C)CC2=CN=C3C(=N2)C(=NC(=N3)N)N
PubChem CID	15459594

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	3 / 11
TPSA	185 Å²
Synonyms	(2S)-dimethyl 2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioate, PLQS-6, CS-M1821, (2S)-dimethyl2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioate, dimethyl (4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamate, 1,5-Dimethyl N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-L-glutamate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dimethyl?

The CAS Registry Number of Dimethyl is 374777-77-2. It is also known as (2S)-dimethyl 2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioate, PLQS-6, CS-M1821.

What is the molecular formula and molecular weight of Dimethyl?

Dimethyl has the molecular formula C25H27N7O5 and a molecular weight of 505.5 g/mol. Its IUPAC name is dimethyl (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioate.

What is Dimethyl used for?

Dimethyl is supplied as a characterised reference material related to Pralatrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dimethyl can I order?

We supply Dimethyl in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dimethyl?

Yes. Every lot of Dimethyl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dimethyl be shipped internationally?

Yes. We export Dimethyl worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.