Loperamide EP Impurity D

Name: Loperamide EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-022996

About Loperamide EP Impurity D

Vaqora Chemicals supplies Loperamide EP Impurity D, a pharmacopeial impurity of Loperamide registered under CAS number 37743-41-2. Its molecular formula is C29H34N2O2 and its molecular weight is 442.6 g/mol. Its systematic (IUPAC) name is 4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide. Alternative names: Loperamide Impurity D and Loperamide - Impurity D.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Loperamide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Loperamide EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loperamide EP Impurity D
Catalogue No.	VQ-022996
CAS Number	37743-41-2
IUPAC name	4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide
Molecular formula	C₂₉H₃₄N₂O₂
Molecular weight	442.6 g/mol
Exact mass	442.262
Grade	Reference Standard
HSN code	38229090
InChIKey	YNPNRXMADRSSLH-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=CC=C2)O)(C3=CC=CC=C3)C4=CC=CC=C4
PubChem CID	3705191

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	1 / 3
TPSA	43.8 Å²
Synonyms	Loperamide Impurity D, Loperamide - Impurity D, Loperamide hydrochloride specified impurity D, 1-Piperidinebutanamide, 4-hydroxy-N,N-dimethyl-alpha,alpha,4-triphenyl-, Deschloroloperamide, 4-(4-hydroxy-4-phenylpiperidyl)-N,N-dimethyl-2,2-diphenylbutanamide

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loperamide EP Impurity D?

The CAS Registry Number of Loperamide EP Impurity D is 37743-41-2. It is also known as Loperamide Impurity D, Loperamide - Impurity D, Loperamide hydrochloride specified impurity D.

What is the molecular formula and molecular weight of Loperamide EP Impurity D?

Loperamide EP Impurity D has the molecular formula C29H34N2O2 and a molecular weight of 442.6 g/mol. Its IUPAC name is 4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide.

What is Loperamide EP Impurity D used for?

Loperamide EP Impurity D is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loperamide EP Impurity D can I order?

We supply Loperamide EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loperamide EP Impurity D?

Yes. Every lot of Loperamide EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loperamide EP Impurity D be shipped internationally?

Yes. Loperamide EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.