Loratadine-d4

Name: Loratadine-d4
Brand: Vaqora Chemicals
SKU: VQ-038130

About Loratadine-d4

Loratadine-d4 (CAS 381727-27-1) is a stable isotope labelled analogue related to Loratadine offered by Vaqora Chemicals. The compound has the formula C22H23ClN2O2, corresponding to a molecular weight of 386.9 g/mol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Loratadine-d4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Loratadine

View every impurity, metabolite and intermediate we list for Loratadine.

Loratadine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loratadine-d4
Catalogue No.	VQ-038130
CAS Number	381727-27-1
IUPAC name	ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,2,6,6-tetradeuteriopiperidine-1-carboxylate
Molecular formula	C₂₂H₂₃ClN₂O₂
Molecular weight	386.9 g/mol
Exact mass	386.1699
Grade	Reference Standard
HSN code	38229090
InChIKey	JCCNYMKQOSZNPW-IDPVZSQYSA-N
SMILES	[2H]C1(CC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC(N1C(=O)OCC)([2H])[2H])[2H]
PubChem CID	45039666

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	0 / 3
TPSA	42.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loratadine-d4?

The CAS Registry Number of Loratadine-d4 is 381727-27-1.

What is the molecular formula and molecular weight of Loratadine-d4?

Loratadine-d4 has the molecular formula C22H23ClN2O2 and a molecular weight of 386.9 g/mol. Its IUPAC name is ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,2,6,6-tetradeuteriopiperidine-1-carboxylate.

What is Loratadine-d4 used for?

Loratadine-d4 is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loratadine-d4 can I order?

We supply Loratadine-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loratadine-d4?

Yes. Every lot of Loratadine-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loratadine-d4 be shipped internationally?

Yes. We export Loratadine-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.