Nifedipine EP Impurity C

About Nifedipine EP Impurity C

Nifedipine EP Impurity C is a pharmacopeial impurity of Nifedipine carrying the CAS registry number 39562-27-1. Its molecular formula is C12H11NO5 and its molecular weight is 249.22 g/mol. The IUPAC name is methyl 2-[(2-nitrophenyl)methylidene]-3-oxobutanoate. Common synonyms include Nifedipine - Impurity C and methyl 2-(2'-nitrobenzylidene)acetoacetate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Nifedipine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Nifedipine EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nifedipine

View every impurity, metabolite and intermediate we list for Nifedipine.

Nifedipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nifedipine EP Impurity C
Catalogue No.	VQ-026900
CAS Number	39562-27-1
IUPAC name	methyl 2-[(2-nitrophenyl)methylidene]-3-oxobutanoate
Molecular formula	C₁₂H₁₁NO₅
Molecular weight	249.22 g/mol
Exact mass	249.0637
Grade	Reference Standard
HSN code	38229090
InChIKey	APKKCRAKPMSAEI-UHFFFAOYSA-N
SMILES	CC(=O)C(=CC1=CC=CC=C1[N+](=O)[O-])C(=O)OC
PubChem CID	787115

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 5
TPSA	89.2 Å²
Synonyms	Nifedipine - Impurity C, methyl 2-(2'-nitrobenzylidene)acetoacetate, 2-(2-Nitrobenzylidene)-3-oxobutanoic Acid, Methyl Ester, Methyl (E/Z)-2-(2-Nitrobenzylidene)-3-oxobutanoate, Methyl-2-(2-nitrobenzyliden)acetoacetate, Methyl 2-(o-nitrobenzylidene)acetoacetate, 2-(2-nitrobenzylidene)-acetoacetic acid methyl ester, methyl 2-[(2-nitrophenyl)methylene]-3-oxo-butanoate, 2-[(2-Nitrophenyl)methylene]-3-oxo-butanoic aci d methyl ester

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P272, P273, P280, P302 + P352, P321, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nifedipine EP Impurity C?

The CAS Registry Number of Nifedipine EP Impurity C is 39562-27-1. It is also known as Nifedipine - Impurity C, methyl 2-(2'-nitrobenzylidene)acetoacetate, 2-(2-Nitrobenzylidene)-3-oxobutanoic Acid, Methyl Ester.

What is the molecular formula and molecular weight of Nifedipine EP Impurity C?

Nifedipine EP Impurity C has the molecular formula C12H11NO5 and a molecular weight of 249.22 g/mol. Its IUPAC name is methyl 2-[(2-nitrophenyl)methylidene]-3-oxobutanoate.

What is Nifedipine EP Impurity C used for?

Nifedipine EP Impurity C is supplied as a characterised reference material related to Nifedipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nifedipine EP Impurity C can I order?

We supply Nifedipine EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nifedipine EP Impurity C?

Yes. Every lot of Nifedipine EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nifedipine EP Impurity C be shipped internationally?

Yes. Nifedipine EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.