Tryptophan EP Impurity E

About Tryptophan EP Impurity E

Tryptophan EP Impurity E is a pharmacopeial impurity of Tryptophan carrying the CAS registry number 3978-11-8. The compound has the formula C11H12N2O4, corresponding to a molecular weight of 236.22 g/mol. Systematically, it is named (2S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid. Alternative names: Tryptophan - Impurity E and N-Formyl-L-kynurenine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Tryptophan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Tryptophan

View every impurity, metabolite and intermediate we list for Tryptophan.

Tryptophan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tryptophan EP Impurity E
Catalogue No.	VQ-034467
CAS Number	3978-11-8
IUPAC name	(2S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid
Molecular formula	C₁₁H₁₂N₂O₄
Molecular weight	236.22 g/mol
Exact mass	236.0797
Grade	Reference Standard
HSN code	38229090
InChIKey	BYHJHXPTQMMKCA-QMMMGPOBSA-N
SMILES	C1=CC=C(C(=C1)C(=O)C[C@@H](C(=O)O)N)NC=O
PubChem CID	439788

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.3
H-bond donors / acceptors	3 / 5
TPSA	109 Å²
Synonyms	Tryptophan - Impurity E, N-Formyl-L-kynurenine, L-Formylkynurenine, (S)-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid, N'-formyl-L-Kynurenine, Formylkynurenine, Formyl-L-Kynurenine, Formylkynurenine, (S)-, Kynurenine, N'-formyl-, 3-(2-formamidobenzoyl)-L-alanine, (S)-2-Amino-4-(2-formamidophenyl)-4-oxobutanoicacid, (2S)-2-amino-4-[2-(formylamino)phenyl]-4-oxobutanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tryptophan EP Impurity E?

The CAS Registry Number of Tryptophan EP Impurity E is 3978-11-8. It is also known as Tryptophan - Impurity E, N-Formyl-L-kynurenine, L-Formylkynurenine.

What is the molecular formula and molecular weight of Tryptophan EP Impurity E?

Tryptophan EP Impurity E has the molecular formula C11H12N2O4 and a molecular weight of 236.22 g/mol. Its IUPAC name is (2S)-2-amino-4-(2-formamidophenyl)-4-oxobutanoic acid.

What is Tryptophan EP Impurity E used for?

Tryptophan EP Impurity E is supplied as a characterised reference material related to Tryptophan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tryptophan EP Impurity E can I order?

We supply Tryptophan EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tryptophan EP Impurity E?

Yes. Every lot of Tryptophan EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tryptophan EP Impurity E be shipped internationally?

Yes. We export Tryptophan EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.