Diphenhydramine EP Impurity B

Name: Diphenhydramine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-036732

About Diphenhydramine EP Impurity B

Listed under CAS 4024-34-4, Diphenhydramine EP Impurity B is a pharmacopeial impurity of Diphenhydramine available from Vaqora Chemicals. Its molecular formula is C18H24ClNO and its molecular weight is 305.8 g/mol. Common synonyms include Diphenhydramine Impurity B and Dimenhydrinate - Impurity G.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Diphenhydramine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Diphenhydramine EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diphenhydramine

View every impurity, metabolite and intermediate we list for Diphenhydramine.

Diphenhydramine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diphenhydramine EP Impurity B
Catalogue No.	VQ-036732
CAS Number	4024-34-4
IUPAC name	N,N-dimethyl-2-[(4-methylphenyl)-phenylmethoxy]ethanamine;hydrochloride
Molecular formula	C₁₈H₂₄ClNO
Molecular weight	305.8 g/mol
Exact mass	305.1546
Grade	Reference Standard
HSN code	38229090
InChIKey	BNFDLGUZDIWYJK-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)C(C2=CC=CC=C2)OCCN(C)C.Cl
PubChem CID	16206677

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	12.5 Å²
Synonyms	Diphenhydramine Impurity B, Dimenhydrinate - Impurity G, Diphenhydramine - Impurity B, Orphenadrine - Impurity F, Neobenodine, p-Methyl diphenhydramine hydrochloride, Ethylamine, N,N-dimethyl-2-((p-methyl-alpha-phenylbenzyl)oxy)-, hydrochloride, 4-Methyldiphenhydramine Hydrochloride, 2-[(RS)-(4-Methylphenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride, Chlorhydrate de dimethylaminoethoxy-p-tolylphenyl-methane gauche, (+)-N,N-Dimethyl-2-(phenyl(p-tolyl)methoxy)ethylamine hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diphenhydramine EP Impurity B?

The CAS Registry Number of Diphenhydramine EP Impurity B is 4024-34-4. It is also known as Diphenhydramine Impurity B, Dimenhydrinate - Impurity G, Diphenhydramine - Impurity B.

What is the molecular formula and molecular weight of Diphenhydramine EP Impurity B?

Diphenhydramine EP Impurity B has the molecular formula C18H24ClNO and a molecular weight of 305.8 g/mol.

What is Diphenhydramine EP Impurity B used for?

Diphenhydramine EP Impurity B is supplied as a characterised reference material related to Diphenhydramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diphenhydramine EP Impurity B can I order?

We supply Diphenhydramine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diphenhydramine EP Impurity B?

Yes. Every lot of Diphenhydramine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diphenhydramine EP Impurity B be shipped internationally?

Yes. Diphenhydramine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.