Tramadol EP Impurity E

About Tramadol EP Impurity E

Tramadol EP Impurity E is a pharmacopeial impurity of Tramadol carrying the CAS registry number 42036-65-7. The compound has the formula C9H18ClNO, corresponding to a molecular weight of 191.7 g/mol. Common synonyms include Tramadol - Impurity E (Hydrochloride Salt) and Tramadol Impurity E Hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Tramadol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Tramadol EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Tramadol

View every impurity, metabolite and intermediate we list for Tramadol.

Tramadol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tramadol EP Impurity E
Catalogue No.	VQ-042638
CAS Number	42036-65-7
IUPAC name	2-[(dimethylamino)methyl]cyclohexan-1-one;hydrochloride
Molecular formula	C₉H₁₈ClNO
Molecular weight	191.7 g/mol
Exact mass	191.1077
Grade	Reference Standard
HSN code	38229090
InChIKey	CLVHTSWMNNSUSH-UHFFFAOYSA-N
SMILES	CN(C)CC1CCCCC1=O.Cl
PubChem CID	359482

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	20.3 Å²
Synonyms	Tramadol - Impurity E (Hydrochloride Salt), Tramadol Impurity E Hydrochloride, 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride, Dimethyl((2-oxocyclohexyl)methyl)ammonium chloride, 2-((Dimethylamino)methyl)cyclohexanone hydrochloride, (2RS)-, Cyclohexanone, 2-((dimethylamino)methyl)-, hydrochloride (1:1), Cyclohexanone, 2-[(dimethylamino)methyl]-, hydrochloride (1:1), 2-((Dimethylamino)methyl)cyclohexanone hydrochloride, 2-(Bismethyl)aminomethylcyclohexanone Hydrochloride, 2-((Dimethylamino)methyl)cyclohexan-1-one hydrochloride, 2-[(dimethylamino)methyl]cyclohexan-1-one hydrochloride, 2-((Dimethylamino)methyl)cyclohexanonehydrochloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tramadol EP Impurity E?

The CAS Registry Number of Tramadol EP Impurity E is 42036-65-7. It is also known as Tramadol - Impurity E (Hydrochloride Salt), Tramadol Impurity E Hydrochloride, 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride.

What is the molecular formula and molecular weight of Tramadol EP Impurity E?

Tramadol EP Impurity E has the molecular formula C9H18ClNO and a molecular weight of 191.7 g/mol.

What is Tramadol EP Impurity E used for?

Tramadol EP Impurity E is supplied as a characterised reference material related to Tramadol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tramadol EP Impurity E can I order?

We supply Tramadol EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tramadol EP Impurity E?

Yes. Every lot of Tramadol EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tramadol EP Impurity E be shipped internationally?

Yes. Tramadol EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.