Dosulepin EP Impurity A

Name: Dosulepin EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-025384

About Dosulepin EP Impurity A

Listed under CAS 42046-35-5, Dosulepin EP Impurity A is a pharmacopeial impurity of Dosulepin available from Vaqora Chemicals. Its molecular formula is C19H21NOS and its molecular weight is 311.4 g/mol. Its systematic (IUPAC) name is (3E)-N,N-dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine. Common synonyms include Dosulepin Hydrochloride - Impurity A and Dothiepin sulfoxide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Dosulepin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dosulepin

View every impurity, metabolite and intermediate we list for Dosulepin.

Dosulepin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dosulepin EP Impurity A
Catalogue No.	VQ-025384
CAS Number	42046-35-5
IUPAC name	(3E)-N,N-dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine
Molecular formula	C₁₉H₂₁NOS
Molecular weight	311.4 g/mol
Exact mass	311.1344
Grade	Reference Standard
HSN code	38229090
InChIKey	NBNPVRZHUPMVQS-GZTJUZNOSA-N
SMILES	CN(C)CC/C=C/1\C2=CC=CC=C2CS(=O)C3=CC=CC=C31
PubChem CID	5365233

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 3
TPSA	39.5 Å²
Synonyms	Dosulepin Hydrochloride - Impurity A, Dothiepin sulfoxide, Dothiepin S-oxide, Dosulepin sulfoxide, 1-Propanamine, N,N-dimethyl-3-(5-oxidodibenzo(b,E)thiepin-11(6H)-ylidene)-, (E)-, Dosulepin Impurity A, Dosulepin S-oxide, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropylamine S-oxide, 3-Dibenzo(b,e)thiepin-11(6H)-ylidene-N,N-dimethylpropylamine S-oxide, Dothiepin sulphoxide, (3E)-N,N-Dimethyl-3-(5-oxidodibenzo[b,E]thiepin-11(6H)-ylidene)-1-propanamine #, (E)-3-(5-oxo-5

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H370Causes damage to organs

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P316, P301 + P317, P308 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dosulepin EP Impurity A?

The CAS Registry Number of Dosulepin EP Impurity A is 42046-35-5. It is also known as Dosulepin Hydrochloride - Impurity A, Dothiepin sulfoxide, Dothiepin S-oxide.

What is the molecular formula and molecular weight of Dosulepin EP Impurity A?

Dosulepin EP Impurity A has the molecular formula C19H21NOS and a molecular weight of 311.4 g/mol. Its IUPAC name is (3E)-N,N-dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine.

What is Dosulepin EP Impurity A used for?

Dosulepin EP Impurity A is supplied as a characterised reference material related to Dosulepin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dosulepin EP Impurity A can I order?

We supply Dosulepin EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dosulepin EP Impurity A?

Yes. Every lot of Dosulepin EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dosulepin EP Impurity A be shipped internationally?

Yes. Dosulepin EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.