Dorzolamide EP Impurity B

Name: Dorzolamide EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-025381

About Dorzolamide EP Impurity B

Dorzolamide EP Impurity B is a pharmacopeial impurity of Dorzolamide carrying the CAS registry number 120279-90-5. Formula C10H16N2O4S3, molecular weight 324.4 g/mol. Systematically, it is named (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. It is also known as Dorzolamide EP Impurity B (free base) or Dorzolamide, (+/-)-(cis)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Dorzolamide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Dorzolamide EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dorzolamide

View every impurity, metabolite and intermediate we list for Dorzolamide.

Dorzolamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dorzolamide EP Impurity B
Catalogue No.	VQ-025381
CAS Number	120279-90-5
IUPAC name	(4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
Molecular formula	C₁₀H₁₆N₂O₄S₃
Molecular weight	324.4 g/mol
Exact mass	324.0272
Grade	Reference Standard
HSN code	38229090
InChIKey	IAVUPMFITXYVAF-POYBYMJQSA-N
SMILES	CCN[C@@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C
PubChem CID	6604453

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	2 / 7
TPSA	151 Å²
Synonyms	Dorzolamide EP Impurity B (free base), Dorzolamide Hydrochloride - Impurity B (Freebase), Dorzolamide, (+/-)-(cis)-, (+/-)-(cis)-dorzolamide, Dorzolamide impurity B, (+/-)-(Cis)-4R,6R-dorzolamide, rac-cis-Dorzolamide, (4R)-Dorzolamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dorzolamide EP Impurity B?

The CAS Registry Number of Dorzolamide EP Impurity B is 120279-90-5. It is also known as Dorzolamide EP Impurity B (free base), Dorzolamide Hydrochloride - Impurity B (Freebase), Dorzolamide, (+/-)-(cis)-.

What is the molecular formula and molecular weight of Dorzolamide EP Impurity B?

Dorzolamide EP Impurity B has the molecular formula C10H16N2O4S3 and a molecular weight of 324.4 g/mol. Its IUPAC name is (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide.

What is Dorzolamide EP Impurity B used for?

Dorzolamide EP Impurity B is supplied as a characterised reference material related to Dorzolamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dorzolamide EP Impurity B can I order?

We supply Dorzolamide EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dorzolamide EP Impurity B?

Yes. Every lot of Dorzolamide EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dorzolamide EP Impurity B be shipped internationally?

Yes. Dorzolamide EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.