N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-… 441797-83-7

Name: N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide
Brand: Vaqora Chemicals
SKU: VQ-044782

About N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide

Vaqora Chemicals supplies N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide, an impurity of Macitentan registered under CAS number 441797-83-7. With the molecular formula C12H12BrClN4O2S, it has a molar mass of 391.67 g/mol. The IUPAC name is 5-(4-bromophenyl)-6-chloro-N-(ethylsulfamoyl)pyrimidin-4-amine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Macitentan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide
Catalogue No.	VQ-044782
CAS Number	441797-83-7
IUPAC name	5-(4-bromophenyl)-6-chloro-N-(ethylsulfamoyl)pyrimidin-4-amine
Molecular formula	C₁₂H₁₂BrClN₄O₂S
Molecular weight	391.67 g/mol
Exact mass	389.9553
Grade	Reference Standard
HSN code	38229090
InChIKey	LCQWUVFBXGNEBT-UHFFFAOYSA-N
SMILES	CCNS(=O)(=O)NC1=C(C(=NC=N1)Cl)C2=CC=C(C=C2)Br
PubChem CID	21041280

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 6
TPSA	92.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide?

The CAS Registry Number of N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide is 441797-83-7. It is also known as Sulfamide,N-[5-(4-bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethyl-.

What is the molecular formula and molecular weight of N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide?

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide has the molecular formula C12H12BrClN4O2S and a molecular weight of 391.67 g/mol. Its IUPAC name is 5-(4-bromophenyl)-6-chloro-N-(ethylsulfamoyl)pyrimidin-4-amine.

What is N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide used for?

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide can I order?

We supply N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide?

Yes. Every lot of N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide be shipped internationally?

Yes. We export N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-ethylsulfamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.