Dapagliflozin

Name: Dapagliflozin
Brand: Vaqora Chemicals
SKU: VQ-007406

About Dapagliflozin

Dapagliflozin (CAS 461432-26-8) is a high-purity reference standard of Dapagliflozin offered by Vaqora Chemicals. The compound has the formula C21H25ClO6, corresponding to a molecular weight of 408.9 g/mol. The IUPAC name is (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol. Common synonyms include dapagliflozine and LYN-045.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 10 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Dapagliflozin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dapagliflozin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Dapagliflozin

View every impurity, metabolite and intermediate we list for Dapagliflozin.

Dapagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	Dapagliflozin
Catalogue No.	VQ-007406
CAS Number	461432-26-8
Other CAS	960404-48-2
IUPAC name	(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular formula	C₂₁H₂₅ClO₆
Molecular weight	408.9 g/mol
Exact mass	408.134
Grade	Reference Standard
HSN code	38229090
InChIKey	JVHXJTBJCFBINQ-ADAARDCZSA-N
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Cl
PubChem CID	9887712

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	4 / 6
TPSA	99.4 Å²
Synonyms	(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol, dapagliflozine, LYN-045, D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-, (1S)-, D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, Dagagflozin, Forxiga (TN), (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol, C-aryl glucoside, 6, Dapagliflozin (Standard), Dapagliflozin (JAN/USAN/INN), EX-A005

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P263, P264, P264 + P265, P270, P273, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dapagliflozin?

The CAS Registry Number of Dapagliflozin is 461432-26-8. It is also known as (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol, dapagliflozine, LYN-045.

What is the molecular formula and molecular weight of Dapagliflozin?

Dapagliflozin has the molecular formula C21H25ClO6 and a molecular weight of 408.9 g/mol. Its IUPAC name is (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol.

What is Dapagliflozin used for?

Dapagliflozin is supplied as a characterised reference material related to Dapagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dapagliflozin can I order?

We supply Dapagliflozin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dapagliflozin?

Yes. Every lot of Dapagliflozin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dapagliflozin be shipped internationally?

Yes. Dapagliflozin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.