Piperazine N, N-Desethyl Sildenafil

About Piperazine N, N-Desethyl Sildenafil

Piperazine N, N-Desethyl Sildenafil is a metabolite or degradation product of Sildenafil carrying the CAS registry number 466684-88-8. The compound has the formula C20H28N6O4S, corresponding to a molecular weight of 448.5 g/mol. Alternative names: Descarbon Sildenafil and Desethane Sildenafil.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Sildenafil, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Piperazine N, N-Desethyl Sildenafil in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Piperazine N, N-Desethyl Sildenafil
Catalogue No.	VQ-042165
CAS Number	466684-88-8
IUPAC name	4-ethoxy-N-[2-(methylamino)ethyl]-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonamide
Molecular formula	C₂₀H₂₈N₆O₄S
Molecular weight	448.5 g/mol
Exact mass	448.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	DBBKIQJKMPUJFA-UHFFFAOYSA-N
SMILES	CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)NCCNC)OCC)C
PubChem CID	135539056

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	3 / 8
TPSA	135 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Piperazine N, N-Desethyl Sildenafil?

The CAS Registry Number of Piperazine N, N-Desethyl Sildenafil is 466684-88-8. It is also known as Descarbon Sildenafil, Desethane Sildenafil, Sildenafil metabolite (UK-150,564).

What is the molecular formula and molecular weight of Piperazine N, N-Desethyl Sildenafil?

Piperazine N, N-Desethyl Sildenafil has the molecular formula C20H28N6O4S and a molecular weight of 448.5 g/mol. Its IUPAC name is 4-ethoxy-N-[2-(methylamino)ethyl]-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonamide.

What is Piperazine N, N-Desethyl Sildenafil used for?

Piperazine N, N-Desethyl Sildenafil is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Piperazine N, N-Desethyl Sildenafil can I order?

We supply Piperazine N, N-Desethyl Sildenafil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Piperazine N, N-Desethyl Sildenafil?

Yes. Every lot of Piperazine N, N-Desethyl Sildenafil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Piperazine N, N-Desethyl Sildenafil be shipped internationally?

Yes. Piperazine N, N-Desethyl Sildenafil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.