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VAQORATofacitinib
Synonyms: Cp-690 free base · CP-690 · JAK inhibitors: tofacitinib · Tofacitinib (CP-690550,Tasocitinib)
CAS No.477600-75-2
FormulaC16H20N6O
Mol. weight312.37
Catalogue No.VQ-007805
PurityReference Standard
HSN38229090
Tofacitinib (CAS 477600-75-2) – Tofacitinib reference standard. C16H20N6O, MW 312.37. Request a quote: COA, bulk packs and worldwide export.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Tofacitinib
Tofacitinib (CAS 477600-75-2) is a high-purity reference standard of Tofacitinib offered by Vaqora Chemicals. Its molecular formula is C16H20N6O and its molecular weight is 312.37 g/mol. The IUPAC name is 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile. It is also known as Cp-690 free base or CP-690.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
Laboratories use this Tofacitinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tofacitinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Identification & assay
- Method development & validation
- QC reference material
Industries
Related to Tofacitinib
View every impurity, metabolite and intermediate we list for Tofacitinib.
Tofacitinib impuritiesSpecifications & identifiers
| Product name | Tofacitinib |
|---|---|
| Catalogue No. | VQ-007805 |
| CAS Number | 477600-75-2 |
| Other CAS | 540737-29-9 |
| IUPAC name | 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
| Molecular formula | C16H20N6O |
| Molecular weight | 312.37 g/mol |
| Exact mass | 312.1699 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | UJLAWZDWDVHWOW-YPMHNXCESA-N |
| SMILES | C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
| PubChem CID | 9926791 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.5 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 88.9 Ų |
| Synonyms | Cp-690 free base, CP-690, JAK inhibitors: tofacitinib, Tofacitinib (CP-690550,Tasocitinib), 4oti, rac-Tofacitinib, Tofacitinib (CP-690550), racemic-tofacitinib, racemic-Tasocitinib, Tofacitinib (USAN), Tofacitinib Base, 3eyg |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H301Toxic if swallowedH302Harmful if swallowedH311Toxic in contact with skinH315Causes skin irritationH319Causes serious eye irritationH331Toxic if inhaledH335May cause respiratory irritationH351Suspected of causing cancerH360May damage fertility or the unborn childH373May causes damage to organs through prolonged or repeated exposure
Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Tofacitinib?
The CAS Registry Number of Tofacitinib is 477600-75-2. It is also known as Cp-690 free base, CP-690, JAK inhibitors: tofacitinib.
What is the molecular formula and molecular weight of Tofacitinib?
Tofacitinib has the molecular formula C16H20N6O and a molecular weight of 312.37 g/mol. Its IUPAC name is 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile.
What is Tofacitinib used for?
Tofacitinib is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Tofacitinib can I order?
We supply Tofacitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Tofacitinib?
Yes. Every lot of Tofacitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Tofacitinib be shipped internationally?
Yes. Tofacitinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Tofacitinib
We reply within one business day with price, pack options, lead time and documentation.
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