Tofacitinib impurity Z

Name: Tofacitinib impurity Z
Brand: Vaqora Chemicals
SKU: VQ-043536

About Tofacitinib impurity Z

Tofacitinib impurity Z (CAS 477600-76-3) is an impurity of Tofacitinib offered by Vaqora Chemicals. Its molecular formula is C15H21N5O and its molecular weight is 287.36 g/mol. Its systematic (IUPAC) name is 1-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]ethanone. It is also known as Tofacitinib Impurity R or CS-M2283.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Tofacitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tofacitinib impurity Z is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tofacitinib impurity Z
Catalogue No.	VQ-043536
CAS Number	477600-76-3
IUPAC name	1-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]ethanone
Molecular formula	C₁₅H₂₁N₅O
Molecular weight	287.36 g/mol
Exact mass	287.1746
Grade	Reference Standard
HSN code	38229090
InChIKey	FJIVGKFVGCGMFC-MFKMUULPSA-N
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)C
PubChem CID	69222083

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 4
TPSA	65.1 Å²
Synonyms	Tofacitinib Impurity R, 3-PiperidinaMine, 1-acetyl-N,4-diMethyl-N-1H-pyrrolo[2,3-d]pyriMidin-4-yl-, (3R,4R)- (9CI), 1-[(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]ethanone, CS-M2283, 1-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-1-piperidyl]ethanone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tofacitinib impurity Z?

The CAS Registry Number of Tofacitinib impurity Z is 477600-76-3. It is also known as Tofacitinib Impurity R, 3-PiperidinaMine, 1-acetyl-N,4-diMethyl-N-1H-pyrrolo[2,3-d]pyriMidin-4-yl-, (3R,4R)- (9CI), 1-[(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]ethanone.

What is the molecular formula and molecular weight of Tofacitinib impurity Z?

Tofacitinib impurity Z has the molecular formula C15H21N5O and a molecular weight of 287.36 g/mol. Its IUPAC name is 1-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]ethanone.

What is Tofacitinib impurity Z used for?

Tofacitinib impurity Z is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tofacitinib impurity Z can I order?

We supply Tofacitinib impurity Z in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tofacitinib impurity Z?

Yes. Every lot of Tofacitinib impurity Z is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tofacitinib impurity Z be shipped internationally?

Yes. We export Tofacitinib impurity Z worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.