Nicotine EP Impurity F

Name: Nicotine EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-032135

About Nicotine EP Impurity F

Vaqora Chemicals supplies Nicotine EP Impurity F, a pharmacopeial impurity of Nicotine registered under CAS number 494-97-3. With the molecular formula C9H12N2, it has a molar mass of 148.2 g/mol. Systematically, it is named 3-[(2S)-pyrrolidin-2-yl]pyridine. It is also known as (S)-Nornicotine or (S)-3-(Pyrrolidin-2-yl)pyridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Nicotine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nicotine

View every impurity, metabolite and intermediate we list for Nicotine.

Nicotine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nicotine EP Impurity F
Catalogue No.	VQ-032135
CAS Number	494-97-3
IUPAC name	3-[(2S)-pyrrolidin-2-yl]pyridine
Molecular formula	C₉H₁₂N₂
Molecular weight	148.2 g/mol
Exact mass	148.1
Grade	Reference Standard
HSN code	38229090
InChIKey	MYKUKUCHPMASKF-VIFPVBQESA-N
SMILES	C1C[C@H](NC1)C2=CN=CC=C2
PubChem CID	91462

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 2
TPSA	24.9 Å²
Synonyms	(S)-Nornicotine, (S)-3-(Pyrrolidin-2-yl)pyridine, l-Nor-nicotine, 1'-Demethyl nicotine, 1'-demethylnicotine, 2-(3-Pyridyl)pyrrolidine, Pyridine, 3-(2-pyrrolidinyl)-,(S)-, 3-(2-pyrrolidinyl)-(s)-pyridine, Demethylnicotine, (R,S)-Nornicotine, 3-((2S)-2-Pyrrolidinyl)Pyridine, 3-(2-Pyrrolidinyl)pyridine

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nicotine EP Impurity F?

The CAS Registry Number of Nicotine EP Impurity F is 494-97-3. It is also known as (S)-Nornicotine, (S)-3-(Pyrrolidin-2-yl)pyridine, l-Nor-nicotine.

What is the molecular formula and molecular weight of Nicotine EP Impurity F?

Nicotine EP Impurity F has the molecular formula C9H12N2 and a molecular weight of 148.2 g/mol. Its IUPAC name is 3-[(2S)-pyrrolidin-2-yl]pyridine.

What is Nicotine EP Impurity F used for?

Nicotine EP Impurity F is supplied as a characterised reference material related to Nicotine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nicotine EP Impurity F can I order?

We supply Nicotine EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nicotine EP Impurity F?

Yes. Every lot of Nicotine EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nicotine EP Impurity F be shipped internationally?

Yes. Nicotine EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.