Fluorouracil EP Impurity B

About Fluorouracil EP Impurity B

Fluorouracil EP Impurity B is a pharmacopeial impurity of Fluorouracil carrying the CAS registry number 496-76-4. With the molecular formula C4H4N2O3, it has a molar mass of 128.09 g/mol. The IUPAC name is 1,3-diazinane-2,4,5-trione. Common synonyms include 5-hydroxy Uracil and Fluorouracil Related Compound B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Fluorouracil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Fluorouracil EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Fluorouracil

View every impurity, metabolite and intermediate we list for Fluorouracil.

Fluorouracil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Fluorouracil EP Impurity B
Catalogue No.	VQ-022678
CAS Number	496-76-4
IUPAC name	1,3-diazinane-2,4,5-trione
Molecular formula	C₄H₄N₂O₃
Molecular weight	128.09 g/mol
Exact mass	128.0222
Grade	Reference Standard
HSN code	38229090
InChIKey	FQXOOGHQVPKHPG-UHFFFAOYSA-N
SMILES	C1C(=O)C(=O)NC(=O)N1
PubChem CID	96994

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.2
H-bond donors / acceptors	2 / 3
TPSA	75.3 Å²
Synonyms	5-hydroxy Uracil, Fluorouracil Related Compound B, Fluorouracil - Impurity B, Dihydropyrimidine-2,4,5(3H)-trione, 2,4,5(3H)-Pyrimidinetrione, dihydro-, 5-hydroxypyrimidine-2,4(1H,3H)-dione, 5-Hydroxyuracil, Isobarbituric acid, 2,4,5-Trihydroxypyrimidine, Dihydro-2,4,5(3H)-pyrimidinetrione, Isobarbituric acid (VAN), (1h,3h,5h)pyrimidinetrione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fluorouracil EP Impurity B?

The CAS Registry Number of Fluorouracil EP Impurity B is 496-76-4. It is also known as 5-hydroxy Uracil, Fluorouracil Related Compound B, Fluorouracil - Impurity B.

What is the molecular formula and molecular weight of Fluorouracil EP Impurity B?

Fluorouracil EP Impurity B has the molecular formula C4H4N2O3 and a molecular weight of 128.09 g/mol. Its IUPAC name is 1,3-diazinane-2,4,5-trione.

What is Fluorouracil EP Impurity B used for?

Fluorouracil EP Impurity B is supplied as a characterised reference material related to Fluorouracil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fluorouracil EP Impurity B can I order?

We supply Fluorouracil EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fluorouracil EP Impurity B?

Yes. Every lot of Fluorouracil EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fluorouracil EP Impurity B be shipped internationally?

Yes. Fluorouracil EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.