Glycolide

Name: Glycolide
Brand: Vaqora Chemicals
SKU: VQ-013446

About Glycolide

Listed under CAS 502-97-6, Glycolide is a process intermediate or related compound of Sitagliptin available from Vaqora Chemicals. With the molecular formula C4H4O4, it has a molar mass of 116.07 g/mol. Its systematic (IUPAC) name is 1,4-dioxane-2,5-dione. Common synonyms include Glycollide and p-Dioxane-2,5-dione.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Sitagliptin, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Glycolide is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Glycolide
Catalogue No.	VQ-013446
CAS Number	502-97-6
IUPAC name	1,4-dioxane-2,5-dione
Molecular formula	C₄H₄O₄
Molecular weight	116.07 g/mol
Exact mass	116.011
Grade	Reference Standard
InChIKey	RKDVKSZUMVYZHH-UHFFFAOYSA-N
SMILES	C1C(=O)OCC(=O)O1
PubChem CID	65432

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	0 / 4
TPSA	52.6 Å²
Synonyms	Glycollide, p-Dioxane-2,5-dione, 1,4-Dioxan-2,5-dione, 2,5-dioxo-1,4-dioxane, Glycolide,99.9%, Glycolide, >=99%, Acetic acid, bimol. cyclic ester, Acetic acid, hydroxy-, bimol. cyclic ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Glycolide?

The CAS Registry Number of Glycolide is 502-97-6. It is also known as Glycollide, p-Dioxane-2,5-dione, 1,4-Dioxan-2,5-dione.

What is the molecular formula and molecular weight of Glycolide?

Glycolide has the molecular formula C4H4O4 and a molecular weight of 116.07 g/mol. Its IUPAC name is 1,4-dioxane-2,5-dione.

What is Glycolide used for?

Glycolide is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Glycolide can I order?

We supply Glycolide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Glycolide?

Yes. Every lot of Glycolide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Glycolide be shipped internationally?

Yes. Glycolide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.