8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine

Name: 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine
Brand: Vaqora Chemicals
SKU: VQ-036430

About 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine

Listed under CAS 50373-22-3, 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine is an impurity of Clozapine available from Vaqora Chemicals. The compound has the formula C13H8Cl2N2, corresponding to a molecular weight of 263.12 g/mol. Systematically, it is named 3,6-dichloro-11H-benzo[b][1,4]benzodiazepine. Common synonyms include 8,11-Dichloro-10H-dibenzo[b,e][1,4]diazepine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Clozapine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Clozapine

View every impurity, metabolite and intermediate we list for Clozapine.

Clozapine impurities

Specifications & identifiers

Chemical identifiers
Product name	8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine
Catalogue No.	VQ-036430
CAS Number	50373-22-3
IUPAC name	3,6-dichloro-11H-benzo[b][1,4]benzodiazepine
Molecular formula	C₁₃H₈Cl₂N₂
Molecular weight	263.12 g/mol
Exact mass	262.0065
Grade	Reference Standard
HSN code	38229090
InChIKey	SCBOZTWAALXNEK-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=NC3=C(N2)C=CC(=C3)Cl)Cl
PubChem CID	135879883

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	1 / 2
TPSA	24.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine?

The CAS Registry Number of 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine is 50373-22-3. It is also known as 8,11-Dichloro-10H-dibenzo[b,e][1,4]diazepine, (E)-8,11-dichloro-5H-dibenzo[b,e][1,4]diazepine.

What is the molecular formula and molecular weight of 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine?

8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine has the molecular formula C13H8Cl2N2 and a molecular weight of 263.12 g/mol. Its IUPAC name is 3,6-dichloro-11H-benzo[b][1,4]benzodiazepine.

What is 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine used for?

8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine is supplied as a characterised reference material related to Clozapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine can I order?

We supply 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine?

Yes. Every lot of 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine be shipped internationally?

Yes. We export 8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.